68809-65-4

Usage

Uses

Used in Chemical Synthesis:
Ethyl 1,4-dimethyl-1H-pyrazole-3-carboxylate is used as an intermediate in the synthesis of various chemical compounds. Its stability and reactivity make it a valuable component in the production of a range of products.
Used in Pharmaceutical Applications:
Ethyl 1,4-dimethyl-1H-pyrazole-3-carboxylate is used as a building block in the development of pharmaceutical drugs. Its unique structure and properties contribute to the creation of new and effective medications for various medical conditions.
Used in Research and Development:
Ethyl 1,4-dimethyl-1H-pyrazole-3-carboxylate is used as a research compound in the study of pyrazole chemistry and its potential applications in various fields, including materials science and drug discovery.
Used in Safety and Handling:
Ethyl 1,4-dimethyl-1H-pyrazole-3-carboxylate is used as a reference material for understanding the safety measures and handling procedures required when working with potentially hazardous chemical substances. This knowledge is crucial for ensuring the safe use and disposal of such compounds in both industrial and laboratory settings.

Upstream product

• 6076-12-6 ethyl 4-methyl-1H-pyrazole-5-carboxylate 
• 74-88-4 methyl iodide 
• 64-17-5 ethanol 
• 7339-53-9 methyl hydrazine hydrochloride 
• 121781-57-5 (E)-1,1,1-trichloro-4-ethoxy-3-methylbut-3-en-2-one 
• 594-27-4 tetramethylstannane 

Downstream Products

• 1616931-07-7 C₁₅H₁₇ClN₂O₃ 
• 1616930-75-6 C₁₈H₂₂N₂O₃ 
• 89202-86-8 N-Phenyl-1,4-dimethylpyrazole-3-carboxamide 

Relevant academic research and scientific papers

AMIDO COMPOUNDS AS AhR MODULATORS

Provided herein are compounds, compositions and methods of using the compounds and compositions for the treatment of diseases modulated, as least in part, by AhR. The compounds are represented by formulae Formula (I), (II), (III), (iv): wherein the letters and symbols a, b, c, d, e, f, g, Z, R1b, R2a and R2b have the meanings provided in the specification.

PYRAZOLYL-BASED CARBOXAMIDES AS CRAC INHIBITORS

The invention relates to pyrazolyl-based carboxamide compounds useful as ICRAC inhibitors, to pharmaceutical compositions containing these compounds and to these compounds for the use in the treatment and/or prophylaxis of diseases and/or disorders, in particular inflammatory diseases and/or inflammatory disorders.

Haloacetylated enol ethers. 11 [16]. Synthesis of 1-methyl- and 1- phenyl pyrazole-3(5)-ethyl esters. A one-pot procedure

A one-pot synthesis of 1-methyl- and 1-phenylpyrazole-3(5)-ethyl esters 2,3a-e by the cyclocondensation of β-alkoxyvinyl trichloromethyl ketones 1a- e with methyl and phenyl hydrazine hydrochloride under mild conditions, is reported. A study using compounds la-e with different substituents proved that these are versatile building blocks for the synthesis of pyrazole derivatives, having a 3(5)-ethoxycarbonyl substituent in good yields (60- 89%). The hydrazine and β-alkoxyvinyl trichloromethyl ketone substituent effects on the reaction regiochemistry on the formation of the 1,3- and 1,5- isomer were observed.