6881-49-8

Usage

Uses

Used in Organic Synthesis:
2H-Thiopyran-3,5(4H,6H)-dione is utilized as a key intermediate in the synthesis of various organic compounds. Its structural features allow for the development of a wide range of chemical entities, making it a valuable component in the creation of novel molecules with potential applications across different industries.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 2H-Thiopyran-3,5(4H,6H)-dione is employed as a precursor for the synthesis of pharmaceuticals. Its unique properties and reactivity contribute to the design and development of new drugs, particularly those targeting specific biological pathways or diseases.
Used in Drug Discovery and Development:
2H-Thiopyran-3,5(4H,6H)-dione is used as a starting material for the exploration of new drug candidates. Its chemical properties make it an interesting target for modification, allowing researchers to investigate structure-activity relationships and optimize the compound's therapeutic potential.
Used in Chemical Research:
2H-Thiopyran-3,5(4H,6H)-dione serves as a subject of interest in chemical research, where its unique properties are studied to understand its reactivity and potential applications in various chemical processes. This research can lead to the discovery of new reactions or methods that leverage the compound's characteristics for practical use.

InChI:InChI=1/C5H6O2S/c6-4-1-5(7)3-8-2-4/h1-3H2

Upstream product

• 61363-62-0 methyl [(2-oxopropyl)sulfanyl]acetate 
• 64878-05-3 ethyl 2-[(2-oxopropyl)sulfanyl]acetate 

Downstream Products

• 79831-28-0 5-anilino-2H-thiopyran-3(6H)-one 
• 402842-45-9 4-chloro-2-(5-oxo-5,6-dihydro-2H-thiopyran-3-ylamino)-benzonitrile 
• 402842-51-7 5-methoxy-2-(5-oxo-5,6-dihydro-2H-thiopyran-3-ylamino)-benzonitrile 
• 402842-43-7 3-chloro-2-(5-oxo-5,6-dihydro-2H-thiopyran-3-ylamino)-benzonitrile 
• 402842-37-9 2-[(5-oxo-5,6-dihydro-2H-3-thiopyranyl)amino]benzonitrile 
• 73269-10-0 5-ethoxy-2H-thiopyran-3(6H)-one 
• 85579-17-5 5H,7H-2,3-dioxa-2a,6-dithia(2a-S^IV)-1,4-diazacyclopentindene 
• 85579-26-6 5H,7H-2,3-Dioxa-2aλ⁴,6-dithia-1,4-diaza-cyclopenta[cd]indene 6-oxide 
• 85579-27-7 5H,7H-2,3-Dioxa-2aλ⁴,6-dithia-1,4-diaza-cyclopenta[cd]indene 6,6-dioxide 
• 95502-26-4 5H-Thiopyrano<4,3-d>isoxazol-4(7H)-one 
• 95502-23-1 2-Phenyl-6H-thiopyrano<3,4-d>pyrimidin-5(8H)-one 
• 95502-19-5 1-Phenyl-5,7-dihydrothiopyrano<3,4-c>pyrazol-4(1H)-one 
• 95502-20-8 1-p-Chlorophenyl-5,7-dihydrothiopyrano<3,4-c>pyrazol-4(1H)-one 
• 95502-21-9 1-p-Bromophenyl-5,7-dihydrothiopyrano<3,4-c>pyrazol-4(1H)-one 

Relevant academic research and scientific papers

Highly potent HIV-1 protease inhibitors with novel tricyclic P2 ligands: Design, synthesis, and protein-ligand X-ray studies

The design, synthesis, and biological evaluation of a series of HIV-1 protease inhibitors incorporating stereochemically defined fused tricyclic P2 ligands are described. Various substituent effects were investigated to maximize the ligand-binding site interactions in the protease active site. Inhibitors 16a and 16f showed excellent enzyme inhibitory and antiviral activity, although the incorporation of sulfone functionality resulted in a decrease in potency. Both inhibitors 16a and 16f maintained activity against a panel of multidrug resistant HIV-1 variants. A high-resolution X-ray crystal structure of 16a-bound HIV-1 protease revealed important molecular insights into the ligand-binding site interactions, which may account for the inhibitor's potent antiviral activity and excellent resistance profiles.

The Synthesis and Electrochemical Properties of Some Novel Photosynthesis Electron Acceptors

A range of dioxathiadiaza heteropentalenes have been prepared and their electrochemical properties have been studied by cyclic voltammetry and e.s.r. spectroscopy.It has been found that these compounds form stable anion radicals in the absence of oxygen and have half-peak reduction potentials in the same range as the bypyridinium compounds such as paraquat (methyl viologen) or diquat.