6882-01-5

Basic information

• Product Name: RENARDINE
• Synonyms: SENKIRKIN;RENARDINE;(1,6)Dioxacyclododecino(2,3,4-gh)pyrrolizinium, 3-ethylidene-2,3,4,5,6,7,9,11,13,14,14A,14B-dodecahydro-6,14B-dihydroxy-5,6,12-trimethyl-2,7-dioxo-, (3Z,5R,6R,14ar,14bs)-(partial)-
• CAS NO: 6882-01-5
• Molecular Formula: C19H27NO6
• Molecular Weight: 0
• Mol File: 6882-01-5.mol
• Article Data: 0

Chemical Properties

• Melting Point: 197°C
• Appearance: /
• CAS DataBase Reference: RENARDINE(CAS DataBase Reference)
• NIST Chemistry Reference: RENARDINE(6882-01-5)
• EPA Substance Registry System: RENARDINE(6882-01-5)

Safety Data

• Statements: 25-68
• Safety Statements: 1-22-45
• RIDADR: 1544
• Hazardous Substances Data: 6882-01-5(Hazardous Substances Data)

Usage

Description

RENARDINE is a hepatotoxic alkaloid derived from Senecio renardi and Nardosmia laevogata. It forms colorless, irregular crystals when recrystallized from ethanol and exhibits slight levorotatory properties with [α]D 2.23° (CHCI3). RENARDINE can yield a crystalline picrate with a melting point of 219-220°C, bitartrate with a melting point of 201°C, and the methiodide which decomposes at 194-6°C.

Uses

Used in Pharmaceutical Industry:
RENARDINE is used as a pharmaceutical compound for its hepatotoxic properties. Its unique chemical structure and biological activity make it a potential candidate for the development of drugs targeting liver diseases or conditions.
Used in Research and Development:
RENARDINE is utilized in research and development for studying its chemical properties, potential applications, and effects on biological systems. Its alkaloid nature and hepatotoxicity make it an interesting subject for scientific investigations and the development of new therapeutic agents.
Used in Toxicological Studies:
Due to its hepatotoxic properties, RENARDINE is used in toxicological studies to understand the mechanisms of liver damage and develop potential treatments or countermeasures against liver toxicity caused by various agents.
Used in Quality Control and Analysis:
RENARDINE can be employed as a reference compound in quality control and analysis of natural products, herbal medicines, or other substances containing alkaloids. Its distinct properties and melting points can help in the identification and quantification of similar compounds in various samples.

References

Danilova, Konovalova., J. Gen. Chem., USSR, 20, 1921 (1950) Danilova, Koretskaya, Utkin., ibid, 31, 3815 (1961) Wunderlich., Chem. & Ind., 2089 (1962)

InChI:InChI=1/C19H28NO6/c1-5-13-10-12(2)18(3,23)17(22)25-11-14-6-8-20(4)9-7-15(19(14,20)24)26-16(13)21/h5-6,12,15,23-24H,7-11H2,1-4H3/q+1/b13-5+/t12-,15-,18-,19+,20?/m1/s1