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1-Acetylaspidospermidine-3α,17-diol is an alkaloid that has been isolated from the bark of Aspidosperma chakense Spagazzini. It forms colorless, irregular crystals from aqueous MeOH and exhibits specific optical rotation and UV absorption characteristics. The presence of one phenolic and one non-phenolic hydroxyl group in its structure allows for the formation of a crystalline hydrochloride, which decomposes at a specific temperature range. Additionally, the oxalate salt of this alkaloid can be crystallized from Et20-MeOH with a melting point of 212-214°C (dec.).

6882-72-0

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6882-72-0 Usage

Uses

1-Acetylaspidospermidine-3α,17-diol has potential applications in various industries, including pharmaceutical, chemical, and research sectors. Some of its uses are as follows:
Used in Pharmaceutical Industry:
1-Acetylaspidospermidine-3α,17-diol is used as a pharmaceutical compound for its potential therapeutic properties. Its unique structure and functional groups may contribute to the development of new drugs or drug candidates for the treatment of various diseases.
Used in Chemical Research:
1-Acetylaspidospermidine-3α,17-diol is used as a research chemical for studying its chemical properties, reactivity, and potential applications in the synthesis of other compounds. Its unique structure and functional groups make it an interesting subject for chemical investigations.
Used in Natural Product Chemistry:
1-Acetylaspidospermidine-3α,17-diol is used as a natural product for studying its occurrence, distribution, and potential biological activities. Its isolation from the bark of Aspidosperma chakense Spagazzini highlights the importance of exploring natural sources for novel and bioactive compounds.

References

Djerassi et a!., Experientia, 18, 113 (1962) Djerassi et al., 1. Amer. Chem. Soc., 84, 3480 (1962)

Check Digit Verification of cas no

The CAS Registry Mumber 6882-72-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,8,8 and 2 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 6882-72:
(6*6)+(5*8)+(4*8)+(3*2)+(2*7)+(1*2)=130
130 % 10 = 0
So 6882-72-0 is a valid CAS Registry Number.
InChI:InChI=1/C21H28N2O3/c1-3-20-8-5-10-22-11-9-21(19(20)22)14-6-4-7-15(25)17(14)23(13(2)24)18(21)16(26)12-20/h4,6-7,16,18-19,25-26H,3,5,8-12H2,1-2H3/t16-,18+,19+,20+,21+/m0/s1

6882-72-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name Spegazzinine

1.2 Other means of identification

Product number -
Other names Aspidospermidine-3,17-diol,1-acetyl-,(3alpha)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6882-72-0 SDS

6882-72-0Downstream Products

6882-72-0Relevant academic research and scientific papers

Divergent total syntheses of (-)-aspidospermine and (+)-spegazzinine

Lajiness, James P.,Jiang, Wanlong,Boger, Dale L.

, p. 2078 - 2081 (2012/06/18)

Divergent total syntheses of (+)-spegazzinine (1) and (-)-aspidospermine (2) and their extensions to the synthesis of C19-epi-aspidospermine and C3-epi-spegazzinine are detailed, confirming the relative stereochemistry and establishing the absolute configuration of (+)-spegazzinine. A powerful intramolecular [4 + 2]/[3 + 2] cycloaddition cascade of a 1,3,4-oxadiazole provided the pentacyclic skeleton and all the requisite stereochemistry of the natural products in a single reaction that forms three rings, four C-C bonds, and five stereocenters.

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