688309-06-0

Basic information

• Product Name: 2-(3-phenoxyphenyl)-3,4-dihydroquinazolin-4-one
• Synonyms: 2-(3-phenoxyphenyl)-3,4-dihydroquinazolin-4-one
• CAS NO: 688309-06-0
• Molecular Weight: 314.343
• Mol File: 688309-06-0.mol

Chemical Properties

• CAS DataBase Reference: 2-(3-phenoxyphenyl)-3,4-dihydroquinazolin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-phenoxyphenyl)-3,4-dihydroquinazolin-4-one(688309-06-0)
• EPA Substance Registry System: 2-(3-phenoxyphenyl)-3,4-dihydroquinazolin-4-one(688309-06-0)

Safety Data

• Hazardous Substances Data: 688309-06-0(Hazardous Substances Data)

Upstream product

• 119072-55-8 tert-butylisonitrile 
• 13826-35-2 3-Phenoxybenzyl alcohol 
• 28144-70-9 anthranilic acid amide 

Downstream Products

• 1388188-14-4 C₂₂H₁₆N₂O₄ 

Relevant articles and documents

Temperature-controlled synthesis of N-acyl anthranilamides and quinazoline-4ones via Pd-catalysed cascade consisting of isocyanide insertion

A one step synthesis of functionlized N-acyl anthranilamide via Pd-catalyzed carboxamidation of o-halo substituted N-phenylamide consisting of isocyanide insertion followed by oxidation of the imine intermediate has been achived successfully. Furthermore,

Metal-free oxidative cyclization of 2-amino-benzamides, 2-aminobenzenesulfonamide or 2-(aminomethyl)anilines with primary alcohols for the synthesis of quinazolinones and their analogues

A general metal-free oxidative cyclization process has been developed for the synthesis of quinazolinones, benzothiadiazines and quinazolines. By this protocol, a range of substituted 2-aminobenzamides, 2-aminobenzenesulfonamide and 2-(aminomethyl)anilines react with various alcohols, leading to the desired annulated products smoothly. This protocol features many advantages as broad substrate scope, mild reaction conditions, low environmental pollution, high atom-economy and good to excellent yields.

Potassium hydroxide-promoted transition-metal-free synthesis of 4(3H)-quinazolinones

We have developed a KOH-promoted transition-metal-free synthesis of 2-substituted 4(3H)-quinazolinones from anthranilamides and benzyl alcohols or cinnamyl alcohol with air as oxidant. The protocol is simple, practical, and cost saving. Graphical abstract: [Figure not available: see fulltext.]