688362-51-8Relevant articles and documents
Intermolecular, Branch-Selective, and Redox-Neutral Cp*IrIII-Catalyzed Allylic C?H Amidation
Knecht, Tobias,Mondal, Shobhan,Ye, Jian-Heng,Das, Mowpriya,Glorius, Frank
supporting information, p. 7117 - 7121 (2019/04/30)
Herein, we report the redox-neutral, intermolecular, and highly branch-selective amidation of allylic C?H bonds enabled by Cp*IrIII catalysis. A variety of readily available carboxylic acids were converted into the corresponding dioxazolones and efficiently coupled with terminal and internal olefins in high yields and selectivities. Mechanistic investigations support the formation of a nucleophilic IrIII–allyl intermediate rather than the direct insertion of an Ir–nitrenoid species into the allylic C?H bond.
Enantioselective synthesis of 1-aryl-2-propenylamines: A new approach to a stereoselective synthesis of the Taxol side chain
Castagnolo, Daniele,Armaroli, Silvia,Corelli, Federico,Botta, Maurizio
, p. 941 - 949 (2007/10/03)
A variety of substituted 1-aryl-2-propenylamines of high enantiomeric purity were prepared via lipase-catalysed resolution of the corresponding racemates. (R)-1-Phenyl-2-propenylamine was further synthesised into (2R,3S)-3-benzoylamino-2-hydroxy-3-phenylpropanoic acid methyl ester, the side chain of Taxol.
