688363-66-8

Basic information

• Product Name: 1-BOC-2,6-DIMETHYL-PIPERAZINE
• Synonyms: 1-BOC-2,6-DIMETHYL-PIPERAZINE;tert-butyl 2,6-diMethylpiperazine-1-carboxylate;1-Boc-2,6-diMethylpiperaz...;1-Piperazinecarboxylic acid, 2,6-diMethyl-, 1,1-diMethylethyl ester;2,6-Dimethyl-1-piperazinecarboxylic acid tert-butyl ester
• CAS NO: 688363-66-8
• Molecular Formula: C11H22N2O2
• Molecular Weight: 214.3
• Mol File: 688363-66-8.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 279.7±15.0 °C(Predicted)
• Appearance: /
• Density: 0.970±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C(protect from light)
• PKA: 8.53±0.60(Predicted)
• CAS DataBase Reference: 1-BOC-2,6-DIMETHYL-PIPERAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BOC-2,6-DIMETHYL-PIPERAZINE(688363-66-8)
• EPA Substance Registry System: 1-BOC-2,6-DIMETHYL-PIPERAZINE(688363-66-8)

Safety Data

• Hazardous Substances Data: 688363-66-8(Hazardous Substances Data)

Usage

General Description

1-BOC-2,6-DIMETHYL-PIPERAZINE, also known as tert-butyl 2,6-dimethylpiperazine-1-carboxylate, is a chemical compound belonging to the group of piperazines. It is primarily noted for its usage in the field of organic chemistry, more specifically in the synthesis and reaction of various organic compounds due to the presence of the piperazine ring in its molecular structure. Known by its CAS number 220246-20-6, it is characterized by a molecular formula of C10H20N2O2. It is typically presented as an off-white crystalline solid. As with any chemical compound, it needs to be properly handled and stored, following safety guidelines to avoid potential hazards.

Upstream product

• 623585-97-7 benzyl (3S,5R)-3,5-dimethylpiperazine-1-carboxylate 
• 21655-48-1 cis-2,6-dimethylpiperazine 
• 2080367-38-8 4-benzyl 1-(tert-butyl) (2R,6S)-2,6-dimethylpiperazine-1,4-dicarboxylate 
• 1207455-37-5 benzyl 4-(t-butoxycarbonyl)-3,5-dimethylpiperazine-1-carboxylate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 108-49-6 3,5-dimethylpiperazine 

Downstream Products

• 1610520-52-9 tert-butyl 4-((7-(3,4-dimethoxyphenyl)-5-methyl-4-oxo-4,5-dihydrothieno[3,2-c]pyridin-2-yl)methyl)-2,6-dimethylpiperazine-1-carboxylate 

Relevant articles and documents

JAK1 SELECTIVE INHIBITORS

Disclosed herein are compounds of Formula (I), and pharmaceutically acceptable salts thereof, wherein R1-R8 have any of the meanings defined herein. Also disclosed are pharmaceutical compositions comprising compounds of Formula (I) and methods of using the same.

FUSED TRICYCLIC AMIDE COMPOUNDS AS MULTIPLE KINASE INHIBITORS

Provided are fused tricyclic amide compounds, pharmaceutical compositions comprising at least one such fused tricyclic compound, processes for the preparation thereof, and the use thereof in therapy. Disclosed herein are certain tricyclic amide compounds that can be useful for inhibiting multiple (specifically BRAF and/or EGFR-T790M) kinases and for treating disorders mediated thereby.

DIHYDROPYRIDOPHTHALAZINONE INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE (PARP)

A compound having the structure set forth in Formula (I) and Formula (II): wherein the substituents Y, Z, A, B, R1, R2, R3, R4 and R5 are as defined herein. Provided herein are inhibitors of poly(ADP-ribose)polymerase activity. Also described herein are pharmaceutical compositions that include at least one compound described herein and the use of a compound or pharmaceutical composition described herein to treat diseases, disorders and conditions that are ameliorated by the inhibition of PARP activity.