688364-59-2

Upstream product

• 688364-58-1 methyl 4-methyl-5-phenylsulfanyl-(E,4S)-2-pentenoate 

Downstream Products

• 688364-60-5 (2S,3S,4S)-5-Benzenesulfinyl-2-bromo-3-hydroxy-4-methyl-pentanoic acid methyl ester 
• 688364-63-8 (2R,3S,4S)-2-Azido-3-(tert-butyl-dimethyl-silanyloxy)-4-methyl-5-phenylsulfanyl-pentanoic acid methyl ester 
• 688364-62-7 (2S,3S,4S)-2-Bromo-3-(tert-butyl-dimethyl-silanyloxy)-4-methyl-5-phenylsulfanyl-pentanoic acid methyl ester 
• 688364-61-6 (2S,3S,4S)-2-Bromo-3-hydroxy-4-methyl-5-phenylsulfanyl-pentanoic acid methyl ester 

Relevant academic research and scientific papers

Stereoselective synthesis of (2R,3R) and (2R,3S)-3-hydroxyleucines

A stereoselective synthesis of (2R,3R) and (2R,3S)-3-hydroxyleucine is disclosed. The key step of the reaction sequence involves, stereo- and regioselective bromohydration of 7, using a brominating agent derived in situ from N-bromosuccinimide and 2,6-lutidine, via intramolecular sulfinyl group participation.