688365-07-3

Upstream product

• 688364-84-3 (1R,3S)-3-[(1S,4R)-2-oxobornane-10-sulfenyl]-1-phenyl-1-hexanol 
• 71242-58-5 (1S,2R,4R)-(-)-10-mercaptoisoboneol 
• 42925-43-9 (E)-1-phenylhex-2-en-1-one 

Downstream Products

• 688365-11-9 (1R,3S)-S-(1-methoxymethoxy-1-phenylhex-3-yl) thioformate 
• 688365-09-5 (1R,4S)-3-[(1R,3S)-1-methoxymethoxy-1-phenylhexylsulfanylmethylene]-2,2-dimethyl-bicyclo[2.2.1]heptane 

Relevant academic research and scientific papers

Diastereo- and enantioselective synthesis of anti-1,3-mercapto alcohols from α,β-unsaturated ketones via tandem Michael addition-MPV reduction

A new and effective asymmetric synthesis of anti-1,3-mercapto alcohols 3 from α,β-unsaturated ketones 1 utilizing tandem Michael addition-Meerwein-Ponndorf-Verley (MPV) reduction is described. Transformation of the MPV products anti-4 via the Wagner-Meerwein rearrangement was optimized under acidic or basic conditions to afford 1,3-mercapto alcohols anti-3, depending on the substituent R2 of 4.