68860-35-5

Upstream product

• 90-02-8 salicylaldehyde 
• 89-95-2 2-methyl-benzyl alcohol 
• 23731-06-8 5-(chloromethyl)salicylaldehyde 
• 603-35-0 triphenylphosphine 

Downstream Products

• 68860-34-4 2-hydroxy-5-vinylbenzaldehyde 
• 70311-00-1 triphenyl-(1',3',3'-trimethyl-1',3'-dihydro-spiro[chromene-2,2'-indol]-6-ylmethyl)-phosphonium; chloride 

Relevant academic research and scientific papers

Zinc (II) complex with a cationic Schiff base ligand: Synthesis, characterization, and biological studies

A cationic Schiff base ligand, TSB (L) and its Zn (II) complex (1) were synthesized and characterized by using CHN, 1H-NMR, FT-IR, UV, LC-MS, and X-ray methods. Their ability to inhibit topoisomerase I, DNA cleavage activities, and cytotoxicity

Rhodium(III)-Catalyzed C-H/N-H Alkyne Annulation of Nonsymmetric 2-Aryl (Benz)imidazole Derivatives: Photophysical and Mechanistic Insights

Rhodium(III) catalysis enabled C-H/N-H alkyne annulation of nonsymmetric imidazole derivatives. This study encompasses the synthesis of imidazoles from a naturally occurring quinoidal compound and their use for the preparation of rigid π-extended imidazole derivatives with outstanding fluorescence. Our study also brings to light the photophysical aspects and the mechanism of the reaction studied via computational calculations. This method provided an efficient and versatile tool for the synthesis of fluorescent compounds with a wide range of chemical and biological applications.

Novel metal complexes for D-(A-π-A)2 motif dye sensitizer: Synthesis and photovoltaic application

Four metal complexes BDTT-PCd, BDTT-PZn, BDTT-PCu, and BDTT-PCo with the symmetrical structure were designed, synthesized, and characterized, which would be used as D-(A-π-A)2 motif dye sensitizers. These complexes adopt Cd(II), Zn(II), Cu(II), and Co(II) complexes as auxiliary electron acceptors (A), thienylbenzo[1,2-b:4,5-b′]dithiophene (BDTT) as electron donor (D), and the 8-quinolinol derivative as the π bridge and the acceptor (A) of D-(A-π-A)2 motif dye sensitizers. The photophysical, electrochemical, and photovoltaic properties of these complexes have been investigated. The four complexes-based dye-sensitized solar cells (DSSCs) device exhibited a short-circuit photocurrent density (Jsc) of 17.51, 17.02, 15.07, and 14.38 mA cm?2 and an attractive power conversion efficiency (η) of 8.82%, 8.32%, 8.03%, and 7.55%, respectively, under the AM 1.5 irradiation (100 mW cm?2). The photovoltaic conversion efficiency (PCE) and the short-circuit photocurrent density (Jsc) of BDTT-PCd, BDTT-PZn, BDTT-PCu, and BDTT-PCo are sequentially reduced; it attributed to the difference of the electron-withdrawing ability of the auxiliary acceptor resulted by the difference of coordination abilities of metal ions Cd(II), Zn(II), Cu(II), and Co(II) with ligand. These results provide strong evidence that D-(A-π-A)2 motif complexes has great potential as promising photosensitizers in the applications of DSSCs.

Benzimidazole derivative and 8-hydroxyquinoline derivative cadmium complex dye sensitizer as well as preparation method and application thereof

The invention relates to a D (-A-pi-A) 2 type benzimidazole derivative and 8-hydroxyquinoline derivative cadmium complex dye sensitizer (BDTT-bi-Cd) as shown in a formula 1 as well as a preparation method and application of the BDTT-bi-Cd. The dye sensitizer is a D (-A-pi-A) 2 type complex synthesized by reacting benzimidazole containing functional groups such as an auxiliary electron acceptor (A), a pi bridge, a main electron acceptor (A) and an anchoring group with a 8-hydroxyquinoline derivative cadmium complex and an electron donor (D) benzodithiophene bithiophene (BDTT) through a Heck coupling reaction. Experiments show that the photovoltaic performance test of a dye-sensitized solar cell with the BDTT-bi-Cd as the dye sensitizer shows good effects that the photoelectric conversion efficiency (PCE) reaches 8.40%, the dye thermal decomposition temperature reaches 320 DEG C or above, the thermal stability is high, the requirements of photovoltaic materials can be met, and the complex dye sensitizer has a certain prospect in the aspect of development and application of the dye-sensitized solar cell. The structure of the complex BDTT-bi-Cd shown in the formula 1 is shown in the specification.

Four D-(A'-pi-A) type-2 imine derivative and metal complex dye sensitizers as well as preparation method and application thereof

The invention relates to four D-(A'-pi-A) type-2 imine derivative and metal complexes BDTT-sf-Cd, BDTT-sf-Zn, BDTT-sf-Cu and BDTT-sf-Ni as shown in a formula 1 as well as a preparation method and application of the four D-(A'-pi-A) type-2 imine derivative and metal complexes. A functionalized imine derivative used as a main ligand is coordinated with metal to form a metal complex which is used asan auxiliary electronic ligand A', benzodithiophene bithiophene (BDTT) is used as an electron donor D, and an imine derivative and metal complex with a D-(A'-pi-A) 2 structure is synthesized through aHeck reaction. An experiment is carried out based on a photovoltaic performance test of a dye-sensitized solar cell taking BDTT-sf-Cd, BDTT-sf-Zn, BDTT-sf-Cu and BDTT-sf-Ni as dye sensitizers, and shows a relatively good effect: the photoelectric conversion efficiency (PCE) reaches 9.85%, 8.99%, 8.21% and 7.95% respectively, the thermal decomposition temperature reaches 120 DEG C or above, and the thermal stability is good. Therefore, the four D-(A'-pi-A) type-2 imine derivative and metal complexes have a certain prospect in the development and application aspects of dye-sensitized solar cells.

Synthesis and X-ray crystal structure of a Molybdenum(VI) Schiff base complex: Design of a new catalytic system for sustainable olefin epoxidation

A targeted new dioxo molybdenum(VI) ONO Schiff base complex was prepared for catalyzing epoxidation of olefins in water. This complex was characterized by FT-IR, NMR, UV–Vis, and X-ray crystallography techniques. DFT calculations are additionally performed to find ground and transition states for finding electronic structure and UV–Vis assignment. Afterward, a new protocol was defined for sustainable catalytic epoxidation of olefin in water using this complex as a green catalyst, and also remarkable results are obtained, such as turn over number up to 1400.

Sterol regulatory element binding protein and acidic nucleoplasm DNA binding protein-1 inhibitor, preparation method and application thereof

The invention discloses a compound which is shown as formula I and can inhibit sterol regulatory element binding protein (Srebp) and acidic nucleoplasm DNA binding protein-1 (And-1, WDHD1), a preparation method and application thereof. RT-PCR (reverse transcription-polymerase chain reaction) and immunoblotting experiments show that the compound can remarkably reduce the expression of a Srebp downstream gene SCD-1 and inhibit the activity of And-1 protein. Further experiments show that the compound has a proliferation inhibition effect on various tumor cells. The compound shown as formula I isexpected to become a novel anti-tumor drug and a tumor chemoradiotherapy sensitizing drug.

Synthesis and Antimicrobial Activity of (3-Formyl-4-hydroxybenzyl)triphenylphosphonium Chloride Acylhydrazones

Abstract: In this study, four novel quaternary phosphonium acylhydrazones, derivatives of (3-formyl-4-hydroxybenzyl)triphenylphosphonium chloride, have been synthesized and their structures elucidated from IR and NMR spectra, and elemental analysis. All synthesized compounds have been tested for their antimicrobial activity, and acylhydrazones have demonstrated selective activity against Gram-positive bacteria strains.

Computational study on non-linear optical property of Wittig based Schiff-Base ligands (both Z & E isomers) & Copper(II) complex

96 new Wittig based Schiff-Base (WSB) ligands (both E & Z conformation) containing fused aromatic rings were designed and screened for NLO property. Wittig based precursor aldehydes were synthesized and spectroscopically confirmed. WSB ligands and their copper(II) complexes were also designed, optimized and their NLO property was studied using a GAUSSIAN09 computer program. For Optimization & Hyperpolarizability (β) calculations, DFT based B3LYP method was applied with LANL2DZ basis set for metal ion and 6-31G* basis set for C, H, N & O atoms. The study presents the Structure-Activity relationship (SAR) between WSB ligands and β. The study revealed that WSB Ligands of the category N2, which are those derived from precursor aldehyde, (2-hydroxy-5-(2-(naphthalen-1-yl)vinyl)benzaldehyde) encoded as PA-2, showed higher β values over N1, which are derived from, 2-hydroxy-5-(2-(naphthalen-1-yl)vinyl)benzaldehyde, encoded as PA-1. Among all ligands, Ligand-14, (E?4-(2-Pyren-1-yl-vinyl)-2-([1,2,4]triazol-4-yliminomethyl)-phenol), of N2 category showed highest β value (6.968 × 10?30 e.s.u). After complexing with Cu(II), encoded as Complex-1 ([(4-(2-Pyren-1-yl-vinyl)-2-([1,2,4]triazol-4-yliminomethyl)-phenoxy)2Cu], which has C2 symmetry, the β value (0.310 × 10?30 e.s.u) unexpectedly decreased. However, it is still high as compared to that of urea (β = 0.091 × 10?30 e.s.u). The output of TD-DFT also supports the obtained results. Different factors affecting β value especially their geometrical isomeric effect were successfully analyzed.

Six-coordinated vanadium(IV) complexes with tridentate task-specific ionic liquid Schiff base ligands: Synthesis, characterization and effect of ionic nature on catalytic activity

By reaction of 5-(chloromethyl)salicylaldehyde with triphenylphosphine and N-methylimidazole in two separate reactions, salicylaldehydetriphenylphosphonium chloride (S2) and salicylaldehydemethylimidazolinium chloride (S3) were prepared. Reaction of 2-(aminomethyl)pyridine with these aldehydes resulted in the task-specific ionic liquid Schiff base ligands L1 and L2, respectively. Then six-coordinated vanadium(IV) Schiff base complexes of VO(acac)L1–4 were synthesized by reactions of these tridentate Schiff base ligands and VO(acac)2 in 1:1 stoichiometry. The aldehydes, ligands and VO(acac)L1–4 complexes were characterized using infrared, 1H NMR, 13C NMR, 31P NMR, UV–visible and mass spectroscopies, as well as elemental analysis. Paramagnetic property of the complexes was also studied using magnetic susceptibility measurements. The complexes were used as catalysts in epoxidation of cyclooctene and oxidation of methylphenyl sulfide and the reaction parameters were optimized. The effect of the ionic nature of the complexes was investigated in these oxidation reactions. The catalytic activity of the complexes could be varied by changing the ionic (cationic or anionic) character of VO(acac)L1–4 catalysts in which counter anion variation showed a greater effect than cationic moiety variation.