688743-60-4Relevant academic research and scientific papers
Synthesis of novel 11-desmethyl analogues of laulimalide by Nozaki-Kishi coupling
Paterson, Ian,Bergmann, Hermann,Menche, Dirk,Berkessel, Albrecht
, p. 1293 - 1295 (2007/10/03)
As a first entry into structurally simplified analogues of the anticancer agent laulimalide, 11-desmethyl compounds 2 and 3 were selected by molecular modeling. The unfavorable diastereoselectivity in the key synthetic step, a Nozaki-Kishi coupling betwee
