688799-51-1Relevant academic research and scientific papers
Development of palladium(II)-catalyzed oxidative cyclization of olefinic keto and/or lactone esters
Hibi, Ayaka,Toyota, Masahiro
, p. 4888 - 4891 (2009)
A highly efficient palladium-catalyzed oxidative cyclization of olefinic keto and/or lactone esters, which features a catalytic cyclization employing one atmosphere of oxygen as a reoxidizing agent, is developed.
Bulky thioureas as new ligands for gold(I)-catalyzed cyclization of acetylenic 1,3-dicarbonyl compounds
Pan, Jie-Hui,Yang, Min,Gao, Qiang,Zhu, Nian-Yong,Yang, Dan
, p. 2539 - 2544 (2007)
We illustrate the first use of bulky N,N′-disubstituted cyclic thioureas as ligands for gold(I) catalysis. X-ray crystal structures of the thiourea-gold(I) complexes presented important information about the nature of the complexation. These complexes wer
Ni(II)-catalyzed Conia-ene reaction of 1,3-dicarbonyl compounds with alkynes
Gao, Qiang,Zheng, Bao-Fu,Li, Jin-Heng,Yang, Dan
, p. 2185 - 2188 (2005)
(Chemical Equation Presented) We have discovered a Ni(II)-catalyzed Conia-ene reaction of 1,3-dicarbonyl compounds with alkynes. In the presence of Ni(acac)2 and Yb(OTf)3, various acetylenic 1,3-dicarbonyl compounds underwent Conia-ene reaction to give mono- and bicyclic olefinic eye opentanes. A mechanism involving the enol-yne-Ni complex formation is proposed and supported by deuterium-labeling experiments.
Gold(I)-Catalyzed Conia-Ene Reaction of β-Ketoesters with Alkynes
Kennedy-Smith, Joshua J.,Staben, Steven T.,Toste, F. Dean
, p. 4526 - 4527 (2007/10/03)
The intramolecular addition of β-ketoesters to unactivated alkynes under neutral conditions and at room temperature is described. The method employs triphenylphosphinegold(I) cation as a catalyst for the formation of exo-methylenecycloalkanes. Both monocyclic and bicyclic cyclopentanes and cyclohexanes can be formed in excellent yields and with good diastereoselectivity. Copyright
