688799-55-5Relevant academic research and scientific papers
Gold(I)-Catalyzed Conia-Ene Reaction of β-Ketoesters with Alkynes
Kennedy-Smith, Joshua J.,Staben, Steven T.,Toste, F. Dean
, p. 4526 - 4527 (2004)
The intramolecular addition of β-ketoesters to unactivated alkynes under neutral conditions and at room temperature is described. The method employs triphenylphosphinegold(I) cation as a catalyst for the formation of exo-methylenecycloalkanes. Both monocyclic and bicyclic cyclopentanes and cyclohexanes can be formed in excellent yields and with good diastereoselectivity. Copyright
