688804-94-6Relevant academic research and scientific papers
Aqueous Phase Organometallic Catalysis Using (MeCp)2Mo(OH) (H2O+. Intramolecular Attack of Hydroxide on Organic Substrates
Breno, Kerry L.,Pluth, Michael D.,Landorf, Christopher W.,Tyler, David R.
, p. 1738 - 1746 (2004)
The hydrolysis of esters and difunctional ethers catalyzed by Cp′2Mo(OH)(H2O)+ (1) (Cp′ = η5-C5H4CH3) and the stoichiometric oxidation of CO to CO2 in the presence of 1 are described. These reactions, combined with the previously reported nitrile hydrations and phosphate esters hydrolyses catalyzed by 1, demonstrate that 1 is an effective homogeneous catalyst for hydration, hydrolysis, and oxidation reactions in aqueous solution under mild conditions (pH ～7, ～80°C). Each reaction is proposed to proceed by intramolecular attack of the hydroxide ligand on a bound substrate. The intramolecular nature of the reaction is supported by the ester hydrolysis activation parameters (ΔH? = 5.9 ± 0.7 kcal/mol and ΔS? = -48 ± 9 eu), the lack of H/D exchange, and the significant increase (106-108) in the rate of hydrolysis over uncatalyzed hydrolysis.
