68885-32-5

Usage

Uses

Used in Pharmaceutical Industry:
(4-chlorophenyl)(pyridin-3-yl)Methanol is used as an intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs. Its unique molecular structure allows for the creation of bioactive compounds with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, (4-chlorophenyl)(pyridin-3-yl)Methanol is employed as an intermediate in the production of agrochemicals, leveraging its structural properties to enhance the effectiveness of these compounds in agricultural applications.
Used in Organic Synthesis:
(4-chlorophenyl)(pyridin-3-yl)Methanol is used as a building block in organic synthesis, facilitating the creation of a variety of organic compounds due to its reactive functional groups and structural diversity.
Used in Drug Development:
(4-chlorophenyl)(pyridin-3-yl)Methanol is utilized in drug development as a key molecule for the synthesis of new materials with potential medicinal properties, taking advantage of its unique structure to explore novel therapeutic avenues.

InChI:InChI=1/C12H10ClNO/c13-11-5-3-9(4-6-11)12(15)10-2-1-7-14-8-10/h1-8,12,15H

Upstream product

• 873-77-8 (4-chlorphenyl)magnesium bromide 
• 626-55-1 3-Bromopyridine 
• 104-88-1 4-chlorobenzaldehyde 
• 14548-44-8 3-(4-chlorobenzoyl)pyridine 

Downstream Products

• 1430341-08-4 C₂₃H₂₂ClN₃O₂ 
• 1430341-09-5 C₂₃H₂₃ClN₄O 
• 1430341-16-4 C₁₉H₂₃ClN₄O 
• 1430341-23-3 C₂₂H₂₂ClN₃ 
• 1430341-21-1 C₂₃H₂₄ClN₃O 
• 38759-96-5 3-[chloro(4-chlorophenyl)methyl]pyridine 
• 1430340-75-2 C₂₁H₂₆ClN₃O₂ 
• 1430340-83-2 C₂₃H₂₂ClN₃O 
• 1430340-87-6 C₁₈H₂₀ClN₃O 
• 1430340-91-2 C₂₂H₂₂ClN₃O₂S 
• 1430340-92-3 C₂₂H₂₈ClN₃O₂S 
• 1430340-93-4 C₂₅H₂₈ClN₃O₂S 
• 1430340-95-6 C₂₂H₂₁Cl₂N₃O₂S 
• 1430340-98-9 C₁₉H₂₄ClN₃O₂S 

Relevant academic research and scientific papers

Pyridine-directed asymmetric hydrogenation of 1 1-diarylalkenes

Highly enantioselective pyridine-directed rhodium-catalyzed asymmetric hydrogenation of challenging 1 1-diarylalkenes is achieved by using [Rh(NBD)DuanPhos]BF4 as a precatalyst. Various types of 2-pyridine substituted 1 1-diarylalkenes could be hydrogenated with good to excellent enantioselectivities which provide an efficient route to the synthesis of pharmaceutically and biologically active compounds containing a 2-pyridyl ethane unit.

Design, structure-activity relationship and in vivo efficacy of piperazine analogues of fenarimol as inhibitors of Trypanosoma cruzi

A scaffold hopping exercise undertaken to expand the structural diversity of the fenarimol series of anti-Trypanosoma cruzi (T. cruzi) compounds led to preparation of simple 1-[phenyl(pyridin-3-yl)methyl]piperazinyl analogues of fenarimol which were investigated for their ability to inhibit T. cruzi in vitro in a whole organism assay. A range of compounds bearing amide, sulfonamide, carbamate/carbonate and aryl moieties exhibited low nM activities and two analogues were further studied for in vivo efficacy in a mouse model of T. cruzi infection. One compound, the citrate salt of 37, was efficacious in a mouse model of acute T. cruzi infection after once daily oral dosing at 20, 50 and 100 mg/kg for 5 days.

Azetidine derivatives, their preparation and pharmaceutical compositions containing them

Compounds of formula: in which R represents a CR1R2, C═C(R5)SO2R6 or C═C(R7)SO2alk radical, their preparation and the pharmaceutical compositions containing them.

Method of regulating the growth of aquatic weeds with pyridine derivatives

A method of regulating the growth of submerged and floating aquatic weeds which comprises adding a 3-substituted pyridinemethane, pyridinemethanol, or derivative thereof, to a body of water containing the submerged and floating aquatic weeds to be regulated, in quantities sufficient to regulate the growth of the said submerged and floating aquatic weeds. The disclosure also relates to novel compositions for carrying out the method.