68890-65-3

Basic information

• Product Name: INTRALIPID
• Synonyms: PHOSPHOLIPID STABILIZED SOYBEAN OIL;INTRALIPID;soybeanoil,phospholipid-stabilized;Lipofundin S 10
• CAS NO: 68890-65-3
• Molecular Weight: 0
• Mol File: 68890-65-3.mol
• Article Data: 0

Chemical Properties

• Appearance: white/emulsion
• Storage Temp.: 2-8°C
• CAS DataBase Reference: INTRALIPID(CAS DataBase Reference)
• NIST Chemistry Reference: INTRALIPID(68890-65-3)
• EPA Substance Registry System: INTRALIPID(68890-65-3)

Safety Data

• WGK Germany: 3
• RTECS: WG4864500
• Hazardous Substances Data: 68890-65-3(Hazardous Substances Data)

Usage

Description

INTRALIPID is a fat emulsion that is commonly used in medical and pharmaceutical applications. It is composed of a mixture of soybean oil, egg yolk phospholipids, and glycerol, which provides a source of essential fatty acids and acts as a carrier for fat-soluble drugs. INTRALIPID is known for its ability to improve the solubility and stability of drugs, making it a valuable component in various formulations.

Uses

Used in Pharmaceutical Industry:
INTRALIPID is used as a carrier for fat-soluble drugs, providing a stable and effective means of delivering these medications to patients.
Used in Tissue Phantom Generation:
INTRALIPID is used as a scattering medium in the creation of tissue phantoms, which are used to study the optical properties of biological tissues and to develop new imaging techniques.
Used in Agarose Gel Phantom:
INTRALIPID is used as a component of agarose gel phantoms to reduce scatter coefficients and background absorption, allowing for more accurate measurements and analysis of optical properties.
Used in Hyperinsulinemic-Euglycemic Clamp Studies:
INTRALIPID is used in infusion into mice in hyperinsulinemic-euglycemic clamp studies to evaluate its effect on nonesterified free fatty acid (NEFA) circulation, providing valuable insights into the role of fatty acids in metabolic processes and potential therapeutic applications.

Biochem/physiol Actions

Intralipid is a lipid emulsion comprising soybean oil. It favors proinflammatory cytokines production and is recommended for the treatment of immune-mediated pregnancy and implantation failure. In parenteral nutrition, intralipid is the source of fats. It elicits protection in heart ischemia-reperfusion injury by inhibiting mitochondrial permeability transition pore opening. Intralipid is an effective alternative for intravenous immunoglobulin and improves bioavailability of platinum based anti-cancer drugs.