68897-94-9Relevant academic research and scientific papers
Synthesis of benzofuryl substituted unsymmetrical ureas under microwave irradiation
Chai, Lan-Qin,Chen, Yony-Xi,Chen, Wei-Peng,Ding, Qi
experimental part, p. 453 - 459 (2009/09/25)
A series of 2-benzofuryl substituted unsymmetrical ureas were synthesized by reactions of benzofuroyl isocyanate, which was prepared from benzofuroyl azide by Curtius rearrangement, with various aromatic amines, 2-amino-5-(benzo-2-furyl)-1,3,4-thiadiazole, and 2-amino-5-aryloxymethylene-1,3, 4-thiadiazoles under microwave irradiation. Compared to conventional methods, this synthesis has the advantages of mild reaction conditions, easy handling, and high yields. The products have been characterized by analytical and spectral (IR and 1H NMR) data.
