689221-55-4Relevant articles and documents
β-Methyl-2-amino-2,3-didesoxyribofuranoside, a Novel Building Block for Backbone Modified Antisense Oligonucleotides
Winkler, Johannes,Urban, Ernst,Noe, Christian R.
, p. 109 - 116 (2007/10/03)
A synthesis of the amino sugar 2-amino-2,3-didesoxyribose is described. Starting from D-glucosamine, β-methylfuranoside was obtained in eight steps in 20% yield. This carbohydrate is a novel building block for nucleosides and for backbone modified antisense oligonucleotides with 2′-5′ amide linkages.