689221-94-1

Upstream product

• 69304-37-6 1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane 
• 263701-23-1 1'-deoxy-β-1'-(2,4-difluorophenyl)-D-ribofuranose 

Downstream Products

• 689222-00-2 Toluene-4-sulfonic acid 2-[(2S,3S,3aR,9aR)-2-(2,4-difluoro-phenyl)-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-3-yloxy]-ethyl ester 
• 689221-98-5 2-[(2S,3S,3aR,9aR)-2-(2,4-Difluoro-phenyl)-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-3-yloxy]-ethanol 
• 689222-02-4 (2S,3S,3aR,9aR)-3-(2-Azido-ethoxy)-2-(2,4-difluoro-phenyl)-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacyclooctene 
• 689221-96-3 [(2S,3S,3aR,9aR)-2-(2,4-Difluoro-phenyl)-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-3-yloxy]-acetic acid methyl ester 

Relevant academic research and scientific papers

The effect of universal fluorinated nucleobases on the catalytic activity of ribozymes

Four fluoro modified universal nucleobases have been synthesized. The universal nucleobases 1 and 2, containing a 2,4-difluorobenzene as nucleobase and a 4,6-difluorobenzimidazole, respectively, were chemically incorporated into a selected hammerhead ribo