689258-25-1

Upstream product

• 637-69-4 4-Methoxystyrene 
• 21678-37-5 N,N,2-trimethylpropionamide 
• 33931-47-4 2-methyl-1-(pyrrolidin-1-yl)propan-1-one 
• 26189-59-3 1-chloro-1-(dimethylamino)-2-methyl-1-propene 

Downstream Products

• 689259-64-1 (2E)-(2,2-dimethyl-3-{4-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy]phenyl}cyclobutylidene)Ethanoic Acid Trifluoroacetate 
• 689259-66-3 (2,2-dimethyl-3-{4-[2-(1-methyl-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-6-yl)ethoxy]phenyl}cyclobutyl)Acetic Acid Trifluoroacetate 
• 689259-68-5 (3,3-dimethyl-2-oxo-4-{4-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy]phenyl}cyclobutyl )acetic acid trifluoroacetate 
• 103-13-9 1-(4-methoxyphenyl)-4-methyl-1-penten-3-one 
• 89445-18-1 2,2-dimethyl-3-(p-methoxyphenyl)cyclopropane-1-carboxylic acid 

Relevant academic research and scientific papers

Friedel-Crafts Alkylation of Aromatics by TiCl 4 -Promoted Ring Cleavage of 3-Arylcyclobutanones

Ring cleavage of 3-arylcyclobutanones and successive Friedel-Crafts alkylation of methoxy- or alkyl-substituted benzene derivatives proceeded to give 3,3-diarylbutan-2-ones by activation with titanium tetrachloride.

A Practical synthesis of 3-Acyl cyclobutanones by [2 〈 2] annulation. Mechanism and utility of the zn(II)-Catalyzed condensation of r-Chloroenamines with electron-deficient alkenes

New conditions for the conversion of simple tertiary amides to R-chloroenamines and their use in Zn(II)-catalyzed cycloaddition reactions with commercial α,β-unsaturated carbonyl compounds allows rapid, regiocontrolled access to 3-acyl cyclobutanones. Rea

Cycloalkyl alkanoic acids as integrin receptor antagonists derivatives

The present invention relates to a class of compounds represented by the Formula I or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising compounds of the Formula I, and methods of selectively inhibiting or antagonizing the αvβ3 and/or αvβ5 integrin.