689283-29-2

Upstream product

• 108-24-7 acetic anhydride 
• 689283-26-9 4-hydroxymethyl-3-methyl-5-[1-methyl-2(RS_S)-phenylsulfinyl-(1S)-ethyl]-(4R,5R)-1,3-oxazolan-2-one 
• 689283-22-5 2-tert-butyldiphenylsilyloxymethyl-3-[1-methyl-2(RS_S)-phenylsulfinyl-(1S)-ethyl]-(2S,3R)-oxirane 
• 628340-18-1 2-bromo-1-tert-butyldiphenylsilyloxy-4-methyl-5(RS_S)-phenylsulfinyl-(2R,3R,4S)-pentan-3-ol 

Downstream Products

• 689283-32-7 3-methyl-5-[1-methyl-2-(4-methylphenylsulfonyloxy)-(1R)-ethyl]-2-oxo-(4R,5R)-1,3-oxazolan-4-ylmethylacetate 

Relevant academic research and scientific papers

Modular and stereoselective formal synthesis of MeBmt, an unusual amino acid constituent of cyclosporin A

A convergent, flexible and stereoselective formal synthesis of MeBmt, the nonproteinogenic amino acid constituent of cyclosporin A is disclosed. The sulfinyl moiety has been exploited as the internal nucleophile to stereo- and regioselectively functionalize an allylic carbamate.