689293-68-3 Usage
Description
Ceftolozane Sulfate is a semi-synthetic antibiotic that belongs to the class of Cephalosporin antibiotics. It is derived from Cephalosporin C Zinc Salt and is characterized by its broad-spectrum antimicrobial activity. Ceftolozane Sulfate exhibits potent antibacterial properties and is effective against a wide range of Gram-negative bacteria, including those that are resistant to other antibiotics.
Uses
Used in Healthcare Industry:
Ceftolozane Sulfate is used as an antibiotic for the treatment of various bacterial infections caused by susceptible Gram-negative bacteria. It is particularly effective against infections such as complicated intra-abdominal infections, urinary tract infections, and hospital-acquired pneumonia. The use of Ceftolozane Sulfate helps in managing multidrug-resistant bacterial infections and reducing the reliance on last-resort antibiotics.
Used in Combination Therapy:
Ceftolozane Sulfate is often used in combination with other antibiotics, such as tazobactam, to enhance its antimicrobial activity and broaden its spectrum of coverage. This combination therapy is particularly useful in treating polymicrobial infections and combating antibiotic resistance.
Used in Research and Development:
Ceftolozane Sulfate is also used in research and development for the discovery of new antibiotics and understanding the mechanisms of action against resistant bacteria. Studies on Ceftolozane Sulfate can provide insights into the development of novel antimicrobial agents and strategies to combat antibiotic resistance.
Check Digit Verification of cas no
The CAS Registry Mumber 689293-68-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,8,9,2,9 and 3 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 689293-68:
(8*6)+(7*8)+(6*9)+(5*2)+(4*9)+(3*3)+(2*6)+(1*8)=233
233 % 10 = 3
So 689293-68-3 is a valid CAS Registry Number.
689293-68-3Relevant articles and documents
A β - lactam compound carboxy and hydroxy protecting group removing method (by machine translation)
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Paragraph 0059; 0060; 0061, (2018/04/02)
The invention discloses a β - lactam compound carboxyl and hydroxyl protecting group removal method, the method is that the carboxyl and/or hydroxyl protected β - lactam compounds in the trichloro acetic acid and carbon is ion absorbent for removing protecting group and gets the role of β - lactam compound deprotected product. The method adopts the trichloro acetic acid instead of trifluoro acetic acid, trichloro acetic acid and phenol or cresol and, anisole together, can greatly reduce the consumption of the trichloroacetic acid; in addition, trichloro acetic acid in the cephalosporin into sodium salt in the follow-up process meets the volunteer fire brigade into chloroform and carbon dioxide, is easy to remove, does not exist the problem of residual of the trichloroacetic acid, the reaction yield is high, relatively few impurities; trichloro acetic acid is inexpensive and environmentally friendly, reduce the cost beneficial to industrial production. (by machine translation)
CEPHEM COMPOUNDS
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Page 36 - 37, (2010/02/06)
The present invention relates to a compound of the formula [I]: wherein R1 is lower alkyl, hydroxy(lower)alkyl or halo(lower)alkyl, and R2 is hydrogen or amino protecting group, or R1 and R2 are bonded together and form lower alkylene or lower alkenylene; R3 is hydrogen or lower alkyl; R4 is ; R5 is carboxy or protected carboxy; and R6 is amino or protected amino, or a pharmaceutically acceptable salt thereof, a process for preparing a compound of the formula [I], and a pharmaceutical composition comprising a compound of the formula [I] in admixture with a pharmaceutically acceptable carrier.
