689297-92-5

Basic information

• Product Name: Imidazo[1,2-a]pyrazin-8(5H)-one, 6,7-dihydro-7-methyl- (9CI)
• Synonyms: Imidazo[1,2-a]pyrazin-8(5H)-one, 6,7-dihydro-7-methyl- (9CI);7-METHYL-6,7-DIHYDROIMIDAZO[1,2-A]PYRAZIN-8(5H)-ONE;6,7-dihydro-7-methyl-Imidazo[1,2-a]pyrazin-8(5H)-one
• CAS NO: 689297-92-5
• Molecular Formula: C₇H₉N₃O
• Molecular Weight: 151.16586
• Product Categories: PIPERIDINE;AMINETERTIARY
• Mol File: 689297-92-5.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Imidazo[1,2-a]pyrazin-8(5H)-one, 6,7-dihydro-7-methyl- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Imidazo[1,2-a]pyrazin-8(5H)-one, 6,7-dihydro-7-methyl- (9CI)(689297-92-5)
• EPA Substance Registry System: Imidazo[1,2-a]pyrazin-8(5H)-one, 6,7-dihydro-7-methyl- (9CI)(689297-92-5)

Safety Data

• Hazardous Substances Data: 689297-92-5(Hazardous Substances Data)

Upstream product

• 689297-90-3 7-methyl-7H-imidazo[1,2-a]pyrazine-8-one 

Downstream Products

• 689297-41-4 4,2'-difluoro-5'-(7-methyl-8-oxo-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazin-3-yl)-biphenyl-2-carbonitrile 

Relevant articles and documents

MIDAZOPYRAZINONES AND IMIDAZOTRIAZINONES DERIVATES AS GABA-A RECEPTOR ANXIOLYTIC

The present invention discloses a compound of formula I, or a pharmaceutically acceptable salt thereof: (I) wherein -U-V- represents -CH=CH-, or -CH2-CH2-, -N=CH- or -CH=N-; X1 represents hydrogen, halogen, C1-6 alkyl, trifluoromethyl or C1-6 alkoxy; X2 represents hydrogen or halogen; Y represents a chemical bond, an oxygen atom, or a -NH- or -OCH2- linkage; Z represents an optionally substituted aryl or heteroaryl group; R1 represents hydrocarbon, a heterocyclic group, trifluoromethyl, -SO2Ra, -SO2NRaRb, -CORa, -CO2Ra or -CONRaRb; and Ra and Rb independently represent hydrogen, hydrocarbon or a heterocyclic group;pharmaceutical compositions comprising it; its use in methods of treatment; use of it in the manufacture of a medicament for treating and/or preventing anxiety; convulsions or a cognitive disorder; and methods of treatment using it.