68935-26-2 Usage
Uses
Used in Pharmaceutical Industry:
S-(-)-3-(1-Methyl-2-pyrrolidinyl)pyridiniuM (+)-Di-p-toluoyl Tartrate is used as a chiral auxiliary for the synthesis of optically pure Nicotine. This is important because the purity and stereochemistry of the compound can significantly impact its pharmacological properties and effectiveness in medical applications. The use of this chiral auxiliary ensures that the desired enantiomer is selectively produced, leading to more potent and safer drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 68935-26-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,8,9,3 and 5 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 68935-26:
(7*6)+(6*8)+(5*9)+(4*3)+(3*5)+(2*2)+(1*6)=172
172 % 10 = 2
So 68935-26-2 is a valid CAS Registry Number.
68935-26-2Relevant academic research and scientific papers
SYNTHESIS AND RESOLUTION OF NICOTINE
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, (2016/11/28)
The present disclosure generally relates to methods of preparing nicotine and resolving R,S nicotine to enrich the (S)(?) enantiomer. The method may comprise combining N-methyl-2-pyrrolidone or a salt thereof with a nicotinate compound in the presence of a solvent and a strong base to form 1-methyl-3-nicotinoyl-2-pyrrolidone or a salt thereof; and reducing the 1-methyl-3-nicotinoyl-2-pyrrolidone or salt thereof in solution with Na2S2O4 to produce racemic nicotine or salt thereof. Resolving the racemic nicotine (or other enantiomeric mixture) may comprise combining the nicotine with (?)-O,O′-di-p-toluoyl-L-tartaric acid (L-PTTA).
