68962-44-7

Downstream Products

• 81750-36-9 C₂₉H₂₈N₄O₅S 
• 81750-58-5 C₃₁H₂₄N₄O₅S 
• 81750-55-2 C₂₉H₂₇BrN₄O₅S 
• 81750-57-4 C₃₁H₃₀N₄O₅S 
• 81750-56-3 C₃₁H₃₁BrN₄O₅S 
• 81750-49-4 4-Bromo-5-((E)-1,2-diphenyl-vinyl)-1-(4-sulfamoyl-phenyl)-1H-pyrazole-3-carboxylic acid ethyl ester 
• 81750-45-0 C₂₉H₂₈N₄O₄S₂ 
• 81750-46-1 C₃₃H₃₄N₄O₄S₂ 
• 81750-37-0 C₃₁H₃₂N₄O₅S 
• 81750-38-1 C₃₃H₃₄N₄O₅S 

Relevant academic research and scientific papers

Synthesis of some substituted pyrazole-3-carboxylic acids with possible hypoglycemic and antimicrobial activity.

Condensation of delta-unsaturated 1.3-diketoesters (1) with 4-substituted arylhydrazines (2) or benzenesulphonyl-hydrazine (8) led to 1-aryl-3-ethoxycarbonyl-5-[alpha-substituted styryl]-pyrazoles (3), and 1-benzenesulphonyl-3-ethoxycarbonyl-5-styryl pyrazole (9). Potassium permanganate oxidation of 3 gave 5-acetyl (or benzoyl)-1-aryl-3-ethoxycarbonyl pyrazoles (6) which on hydrolysis gave the corresponding carboxylic acids (7). Hydrolysis of 3 gave the corresponding acids 4 which on treatment with thionyl chloride followed by ammonia afforded the corresponding carboxamides 5.