Uncarine A is an amorphous alkaloid that was first isolated from Uncaria kawakamii and later found in other Uncaria species as well as in Ourouparia formosan a Matsumara. It is a dextrorotatory compound with a specific rotation of [α]D + 106.5°. The hydrochloride hemihydrate form of uncarine A appears as colorless needles with a melting point of 231°C (decomposition), and its N-acetyl derivative has a melting point of 165°C. The stereochemistry of this alkaloid has been recently revised.
6899-73-6
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Basic information
- Product Name: uncarine A
- Synonyms: uncarine A
- CAS NO:6899-73-6
- Molecular Formula: C21H24N2O4
- Molecular Weight: 368.42626
- EINECS: N/A
- Product Categories: N/A
- Mol File: 6899-73-6.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: 555.2°C at 760 mmHg
- Flash Point: 289.6°C
- Appearance: /
- Density: 1.33g/cm3
- Vapor Pressure: 2.3E-12mmHg at 25°C
- Refractive Index: 1.635
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: uncarine A(CAS DataBase Reference)
- NIST Chemistry Reference: uncarine A(6899-73-6)
- EPA Substance Registry System: uncarine A(6899-73-6)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 6899-73-6(Hazardous Substances Data)
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6899-73-6 Usage
Uses
1. Used in Pharmaceutical Industry:Uncarine A is used as a pharmaceutical compound for its potential therapeutic applications. The alkaloid's unique structure and properties make it a promising candidate for the development of new drugs and treatments.
2. Used in Research and Development:
Uncarine A serves as a valuable research tool for scientists studying the chemical properties, biological activities, and potential applications of alkaloids derived from natural sources. Its isolation and characterization contribute to the understanding of the diverse chemical constituents found in plants and their potential uses in medicine and other industries.
3. Used in Traditional Medicine:
Uncarine A may be used in traditional medicine practices, particularly those that involve the use of Uncaria species and related plants. Its potential therapeutic properties could be harnessed to develop remedies for various ailments and health conditions.
4. Used in Drug Delivery Systems:
Similar to gallotannin, uncarine A could be employed in the development of novel drug delivery systems to enhance its applications and efficacy. Researchers may explore the use of various organic and metallic nanoparticles as carriers for uncarine A delivery, aiming to improve its delivery, bioavailability, and therapeutic outcomes.
References
Raymond-Hamet., Compt. rend., 203, 1383 (1936) Kondo, Ikeda.,]. Pharm. Soc., Japan, 61,416,453 (1941) Kondo, Ikeda., ibid, 62, 15 (1942) Raymond-Hamet., Compt. rend., 230, 1405 (1950) Kondo, Nozoye, Tobita., Chern. Abstr., 49, 15921 (1955) Raymond-Hamet., Compt. rend., 245, 1458 (1957) Hendrickson., J. Amer. Chern. Soc., 84,650 (1962) Revised stereochemistry: Shamma et ai., J. Amer. Chern. Soc., 89, 1739 (1967) Beecham et ai., Chern. Commun., 535 (1967)Check Digit Verification of cas no
The CAS Registry Mumber 6899-73-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,8,9 and 9 respectively; the second part has 2 digits, 7 and 3 respectively.Calculate Digit Verification of CAS Registry Number 6899-73:
(6*6)+(5*8)+(4*9)+(3*9)+(2*7)+(1*3)=156
156 % 10 = 6
So 6899-73-6 is a valid CAS Registry Number.
InChI:InChI=1/C21H24N2O4/c1-12-14-10-23-8-7-21(16-5-3-4-6-17(16)22-20(21)25)18(23)9-13(14)15(11-27-12)19(24)26-2/h3-6,11-14,18H,7-10H2,1-2H3,(H,22,25)/t12-,13+,14-,18+,21+/m1/s1
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uncarine A
