6900-06-7

Usage

Uses

Used in Flavor and Fragrance Industry:
Hexanedioic acid dipropargyl ester is used as a flavoring agent and fragrance ingredient for its distinct sharp, fruity odor, adding unique scents and tastes to various products in this industry.
Used in Polymer and Plastics Production:
Hexanedioic acid dipropargyl ester is also utilized in the production of polymers, plastics, and other industrial applications, where its chemical properties contribute to the formation of desired material characteristics.
Safety Considerations:
It is important to handle Hexanedioic acid dipropargyl ester with care, as it may cause irritation to the skin, eyes, and respiratory system upon exposure. Proper safety measures should be followed to minimize potential health risks during its use in different applications.

InChI:InChI=1/C12H14O4/c1-3-9-15-11(13)7-5-6-8-12(14)16-10-4-2/h1-2H,5-10H2

Upstream product

• 107-19-7 propargyl alcohol 
• 111-50-2 Adipic acid dichloride 
• 124-04-9 Adipic acid 

Downstream Products

• 1384100-13-3 bis((1-benzyl-1H-1,2,3-triazol-4-yl)methyl) adipate 
• 1384100-14-4 bis((1-phenethyl-1H-1,2,3-triazol-4-yl)methyl) adipate 

Relevant academic research and scientific papers

Stumuli-responsive organogel based on poly(N-propargylamide)

The first example for a novel stimuli-responsive organogel that senses external stimuli and undergoes very quick volume change in isotropic organic solvents was demonstrated. It was evidenced that the volume change was driven by the conformational change of the framework between the helical and disordered structures. In addition, it was observed that the volume change occured more rapidly when the solvent was changed from CHCl3 to methanol and that this event could be monitored by the naked eye.

Cross-linked micelle, drug delivery carrier targeting cancer cell and method for preparing the same

The present invention relates to a cancer cell-targeting cross-linked micelle, a drug delivery, and a production method thereof. The cancer cell-targeting cross-linked micelle and the drug delivery can be produced simply by a one-pot click reaction, and can also specifically induce the death of cancer cells by releasing drugs after specifically targeting cancer cells, thereby being useful in pharmaceutical fields.COPYRIGHT KIPO 2017

The first thiol-yne click chemistry approach for the preparation of liquid crystalline elastomers

A thiol-yne click chemistry reaction is presented, for the first time, to prepare liquid crystalline elastomers. The synthetic strategy is based on two liquid crystalline monomers, one bearing an alkyne group and the second bearing two thiol groups, to cr

Regioselective synthesis and antimicrobial studies of ester linked 1,4-disubstituted 1,2,3-bistriazoles

A series of 1,4-disubstituted 1,2,3-bistriazoles was synthesized via click chemistry by cycloaddition of various bisalkynes with benzyl/2-phenylethyl azide. Synthesized triazoles were characterized by IR, 1H NMR, 13C NMR and mass spe

Development of a triazole-cure resin system for composites: Evaluation of alkyne curatives

We are developing a resin system that cures via triazole ring formation (cycloaddition reaction of azides with terminal alkynes) instead of the traditional oxirane/amine reaction. The high exothermicity of the azido/alkyne reaction is expected to yield higher extents of reaction under ambient-cure conditions, making the resin system potentially suitable for out-of-autoclave curing processes. The difunctional azide-terminated resin, di(3-azido-2-hydroxypropyl) ether of bisphenol-A, was selected as the baseline diazide. A number of alkyne crosslinkers were synthesized and characterized, including propiolate esters of di- and trifunctional alcohols, propargyl esters of di- and trifunctional carboxylic acids, propargyl ethers of di- and trifunctional alcohols, and N,N,N′,N′-tetrapropargyl derivatives of primary diamines. Commercially available tripropargyl amine was also studied. Those systems employing a propiolate-based alkyne were found to be much more reactive toward the Huisgen 1,3-dipolar cycloaddition than the propargyl species. Curing energetics as a function of alkyne type, investigated through a dynamic differential scanning calorimetry approach, showed a distinct divide between the averaged activation energies of the propiolate and propargyl-type crosslinkers, 69.2-73.6 kJ/mol versus 82.3-86.4 kJ/mol, respectively. Cured network properties were readily manipulated through the incorporation of varying amounts of di- versus tri- and tetra-functional alkynes or through incorporation of soft alkylene and alkyleneoxy versus rigid aromatic polyalkynes. As expected, mechanical properties, e.g., the temperature of the tan δ peak in dynamic mechanical analysis, were found to increase with increasing crosslink density. These results have allowed us to select the most promising systems for scale-up and fabrication of samples of both pure resin and composites for traditional mechanical property testing, which will be reported in a subsequent paper.

Copper-catalyzed [1,3]-dipolar cycloaddition for the synthesis of macrocycles containing acyclic, aromatic and steroidal moieties

Copper-catalyzed 1,3-dipolar cycloaddition reactions are used for the synthesis of a series of bis(1,2,3-triazole)-containing macrocycles possessing acyclic, aromatic and steroidal fragments. The influence of the nature of the substituents on the diazides