69022-58-8

Upstream product

• 89-58-7 mononitro-p-xylene 
• 69022-57-7 6-acetamido-5,8-dimethylisoquinolin-1(2H)-one 

Downstream Products

• 1049319-14-3 5,8-dimethyl-6-(pyridin-2-ylamino)-2H-isoquinolin-1-one 
• 65222-36-8 5,11-Dimethyl-dipyrido<4,3-b><3,4-f>indol 
• 73323-33-8 10-((γ-(diethylamino)propyl)amino)-6,11-dimethyl-5H-pyrido<3',4':4,5>pyrrolo<2,3-g>isoquinoline 
• 73323-34-9 10-((γ-(dimethylamino)propyl)amino)-6,11-dimethyl-5H-pyrido<3',4':4,5>pyrrolo<2,3-g>isoquinoline 

Relevant academic research and scientific papers

Synthesis and activity of a novel inhibitor of nonsense-mediated mRNA decay

During efforts to prepare the known compound NMDI1, a new tetracyclic compound, called VG1, was prepared in six steps. This compound was found to have good activity as an inhibitor of nonsense-mediated mRNA decay.

Dipyrido [4,3-b] [3,4-f] indoles and process for obtaining them

The invention relates to compounds of formula: STR1 wherein R'1 =H, OH or an alkyl group, preferably a lower alkyl group, alkylthio or alkoxy, an halogen or an amino group, R'2 =H or a lower alkyl group. These compounds have antitumoral and antiviral properties useful for the treatment of cancers.

Photocyclization of 1-(1-Chloroisoquinolin-6-yl)-1H-v-triazolopyridines to 10-Chloro-5H-pyridopyrroloisoquinolines (Azaellipticines)

Whereas thermal cyclization of 1-(5,8-dimethyl-1-oxo-1,2-dihydroisoquinolin-6-yl)-1H-v-triazolopyridine affords 6,11-dimethyl-5H-pyridopyrroloisoquinolin-10(9H)-one which cannot be chlorinated to the corresponding chloro derivativ