69027-37-8

Basic information

• Product Name: Ethanone, 1-(2-hydroxy-3,5-dinitrophenyl)-
• CAS NO: 69027-37-8
• Molecular Formula: C8H6N2O6
• Molecular Weight: 226.145
• Mol File: 69027-37-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-(2-hydroxy-3,5-dinitrophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-(2-hydroxy-3,5-dinitrophenyl)-(69027-37-8)
• EPA Substance Registry System: Ethanone, 1-(2-hydroxy-3,5-dinitrophenyl)-(69027-37-8)

Safety Data

• Hazardous Substances Data: 69027-37-8(Hazardous Substances Data)

Usage

General Description

Ethanone, 1-(2-hydroxy-3,5-dinitrophenyl)- is a chemical compound that is commonly known as Trinitrophenol. It is a yellow crystalline solid with a molecular formula of C8H5N3O8. Trinitrophenol is primarily used in the manufacturing of explosives, dyes, and insecticides. It is highly toxic and poses health risks if ingested, inhaled, or absorbed through the skin. Trinitrophenol is also considered an environmental pollutant and can contaminate soil and water sources. Due to its hazardous properties, strict safety measures should be followed in handling and storing this chemical compound.

Upstream product

• 610-99-1 1-(2-Hydroxy-phenyl)-propan-1-on 
• 118-93-4 o-hydroxyacetophenone 

Downstream Products

• 70977-79-6 3-amino-2-hydroxy-5-nitroacetophenone 
• 70977-90-1 1-(4-methoxy-benzyl)-1H-tetrazole-5-carboxylic acid 3-acetyl-2-hydroxy-5-nitro-anilide 
• 70977-42-3 1H-tetrazole-5-carboxylic acid 3-acetyl-2-hydroxy-5-nitro-anilide 
• 158555-17-0 4',6,8-trinitroflavone 
• 1026723-11-4 1-(2-Hydroxy-3,5-dinitro-phenyl)-3-(4-nitro-phenyl)-propane-1,3-dione 

Relevant articles and documents

Synthesis and Biochemical Evaluation of a Series of Aminoflavones as Potential Inhibitors of Protein-Tyrosine Kinases p56lek, EGFr, and p60v-src

A series of nitroflavones, 8a-p, and their corresponding aminoflavone hydrochloride salts, 10a-p, was synthesized.The preparation of nitroflavones 8b-i,o,p began with commercially available o-hydroxyacetophenones 2b-f which were converted to o-hydroxynitroacetophenones 3a-h via a variety of nitration methods, followed by condensation with nitrobenzyl chlorides and cyclization under acidic condition.The nitroflavones 8a,j-n were prepared by nitration of the corresponding flavones 7a-e.These new compounds were evaluated for their abilities to inhibit the in vitro protein-tyrosine kinase activities of p56lek, EGFr, and p60v-src, and all of the active compounds were amino-substituted flavones.None of the nitroflavones inhibited the enzymes.The most active substance in this series against p56lek was compound 10j, which had an IC50 of 18 μM.When tested versus EGFr, compounds 10a,m displayed IC50's of 8.7 and 7.8 μM, respectively.Against p60v-src, 10a,m showed IC50 values of 28.8 and 38.4 μM, respectively.

Substituted alkylaryl ketones and methods of use as herbicides

Ring and side chain substituted alkylaryl ketones are useful in controlling the growth of germinating and seedling weed grasses and germinating and seedling broadleaf weeds.