690274-17-0Relevant articles and documents
Estrogen receptor ligands. Part 1: The discovery of flavanoids with subtype selectivity
Chen, Helen Y.,Dykstra, Kevin D.,Birzin, Elizabeth T.,Frisch, Katalin,Chan, Wanda,Yang, Yi T.,Mosley, Ralph T.,DiNinno, Frank,Rohrer, Susan P.,Schaeffer, James M.,Hammond, Milton L.
, p. 1417 - 1421 (2007/10/03)
A class of flavanoids exhibiting a high degree of selectivity for ERα over ERβ has been discovered. The most active analogue 6 was found to be 66-fold ERα-selective and demonstrated uterine estradiol antagonism.