69034-11-3

Basic information

• Product Name: Pyrimidine, 2-chloro-5-(trichloromethyl)- (9CI)
• Synonyms: Pyrimidine, 2-chloro-5-(trichloromethyl)- (9CI);2-chloro-5-(trichloromethyl)-Pyrimidine
• CAS NO: 69034-11-3
• Molecular Formula: C₅H₂Cl₄N₂
• Molecular Weight: 231.89478
• Product Categories: PYRIMIDINE
• Mol File: 69034-11-3.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Pyrimidine, 2-chloro-5-(trichloromethyl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrimidine, 2-chloro-5-(trichloromethyl)- (9CI)(69034-11-3)
• EPA Substance Registry System: Pyrimidine, 2-chloro-5-(trichloromethyl)- (9CI)(69034-11-3)

Safety Data

• Hazardous Substances Data: 69034-11-3(Hazardous Substances Data)

Upstream product

• 1780-31-0 2,6-dichloro-5-methylpyrimidine 
• 65-71-4 thymin 
• 22536-61-4 2-chloro-5-methylpyrimidine 

Downstream Products

• 1214344-68-9 2-fluoro-5-trifluoromethylpyrimidine 
• 69034-12-4 2-chloro-5-(trifluoromethyl)pyrimidine 
• 94447-84-4 2-benzylthio-5-trifluoromethylpyrimidine 

Relevant articles and documents

Synthesis method 2 -fluoro -5 -trifluoromethyl pyrimidine

The invention relates to the technical field of drug synthesis, and provides a synthesis method of 2 -fluoro -5 -trifluoromethyl pyrimidine. 5 - Methyluracil is used as a raw material and is subjected to cyclic chlorination reaction. Redox reaction, chlorination reaction and fluorination reaction obtain the target product, the process is simple, the raw materials are cheap and easily available, the yield is high, and no heavy metal pollution is generated in the whole process. In the chlorination reaction, phosphorus oxychloride is used for chlorination, chlorine is used for chlorination in the chlorination reaction, the cost of the chlorination reaction is low, phosphorus pentachloride is used for recycling phosphorus oxychloride in the cyclochlorination reaction, and the reaction cost can be further reduced.

Aryl sulfonamide and sulfonyl compounds as modulators of PPAR and methods of treating metabolic disorders

Aryl sulfonamide and sulfonyl compounds as modulators of peroxisome proliferator activated receptors, pharmaceutical compositions comprising the same, and methods of treating disease using the same are disclosed.

Synthesis of Some 5-Trifluoromethylpyrimidines

5-Trifluoromethyl-2-pyrimidinones have been prepared by selective substitution reactions from 2-chloro-5-methylpyrimidine.

Derivatives of (pyrimidyloxy)phenoxy-alkanecarboxylic acid and herbicidal compositions thereof

A compound of general formula I: STR1 wherein A, B, D, E, and V are independently chosen from hydrogen, halogen, nitro, cyano, thiocyano, amino, alkyl, alkoxy, alkylthio, alkenyl, cycloalkyl, carbalkoxy, phenyl, phenoxy or phenylthio; R1 and R2 are independently hydrogen, alkyl, alkenyl, alkanoyl, or R1 and R2 together are alkylidene; W is carboxy or a functional derivative thereof or CH2 Z wherein Z is halogen, hydroxy, alkoxy, alkylthio, formyl or amino; and X and Y are oxygen or sulfur.