690631-49-3Relevant academic research and scientific papers
Synthesis of nonracemic allylic hydroxy phosphonates via alkene cross metathesis
He, Anyu,Yan, Bingli,Thanavaro, Anchalee,Spilling, Christopher D.,Rath, Nigam P.
, p. 8643 - 8651 (2007/10/03)
Allylic hydroxy phosphonates and their derivatives can be interconverted by using cross metathesis with second generation Grubbs catalyst. The absolute stereochemistry of the starting phosphonate is conserved in the product. Cross metathesis reaction of t
Stereospecific Pd(O)-Catalyzed Malonate Additions to Allylic Hydroxy Phosphonate Derivatives: A Formal Synthesis of (-)-Enterolactone
Yan, Bingli,Spilling, Christopher D.
, p. 2859 - 2862 (2007/10/03)
A combination of cross-metathesis and malonate addition was applied to a formal synthesis of the mammalian lignan enterolactone 5. The cross-metathesis of alkene 6 and phosphonate 3a gave the substituted allylic phosphonate 3d. The palladium-catalyzed add
