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[2-(4-Chlorophenyl)-1,3-thiazol-4-yl]methanamine hydrochloride is a chemical compound that serves as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It is a derivative of thiazole, a heterocyclic compound with a five-membered ring containing sulfur and nitrogen. The incorporation of a chlorophenyl group endows the molecule with unique chemical and biological properties, enhancing its utility in various applications. The hydrochloride salt form of the compound is preferred for its improved solubility in water and ease of handling, making it a significant compound in organic chemistry with practical uses in the pharmaceutical and agrochemical industries.

690632-35-0

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690632-35-0 Usage

Uses

Used in Pharmaceutical Industry:
[2-(4-Chlorophenyl)-1,3-thiazol-4-yl]methanamine hydrochloride is used as a synthetic intermediate for the development of various pharmaceuticals. Its unique chemical structure allows for the creation of new drugs with potential therapeutic applications, such as antibiotics, anti-inflammatory agents, and other medicinal compounds.
Used in Agrochemical Industry:
In the agrochemical industry, [2-(4-Chlorophenyl)-1,3-thiazol-4-yl]methanamine hydrochloride is utilized as a precursor in the synthesis of agrochemicals, including pesticides and herbicides. Its properties contribute to the development of effective and targeted solutions for crop protection and management.
Used in Organic Chemistry Research:
[2-(4-Chlorophenyl)-1,3-thiazol-4-yl]methanamine hydrochloride is also used as a research compound in organic chemistry. Its unique structure and properties make it a valuable tool for studying chemical reactions, mechanisms, and the development of new synthetic methodologies.

Check Digit Verification of cas no

The CAS Registry Mumber 690632-35-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,9,0,6,3 and 2 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 690632-35:
(8*6)+(7*9)+(6*0)+(5*6)+(4*3)+(3*2)+(2*3)+(1*5)=170
170 % 10 = 0
So 690632-35-0 is a valid CAS Registry Number.
InChI:InChI=1/C10H9ClN2S.ClH/c11-8-3-1-7(2-4-8)10-13-9(5-12)6-14-10;/h1-4,6H,5,12H2;1H

690632-35-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name [2-(4-chlorophenyl)-1,3-thiazol-4-yl]methanamine,hydrochloride

1.2 Other means of identification

Product number -
Other names 2'-Amino-[1,1'-biphenyl]-4-carbonitrile

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:690632-35-0 SDS

690632-35-0Upstream product

690632-35-0Downstream Products

690632-35-0Relevant academic research and scientific papers

Design, synthesis, fungicidal activities and structure–activity relationship studies of (?)-borneol derivatives containing 2-aryl-thiazole scaffold

Huang, Danling,Zheng, Shumin,Zhang, Tianyuan,Cheng, Yong-Xian

, (2021)

A series of (-)-borneol derivatives containing 2-aryl-thiazole scaffold were designed, synthesized, and characterized by 1H NMR, 13C NMR, and HRMS. The fungicidal activities of these novel compounds against Fusarium oxysporum, Magnaporthe grisea, Botrytis cinerea, and Penicillium digitatum were evaluated. The results indicated that (1S,2R,4S)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-yl(Z)-4-oxo-4-(((2-phenylthiazol-4-yl)methyl)amino)but-2-enoate (6a) displayed potential fungicidal activities with broad spectrum. Especially, 6a exhibited an IC50 value of 48.5 mg/L against P. digitatum, which has higher fungicidal activity than commercial products hymexazol and amicarthiazol. Moreover, (1S,2R,4S)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-yl-4-oxo-4-(((2-phenylthiazol-4-yl)methyl)amino)butanoate (5a) possesses an IC50 value of 24.3 mg/L against B. cinerea, comparable to hymexazol and far superior to amicarthiazol. Furthermore, the superficial structure–activity relationship was discussed, which might be helpful for discovering novel fungicides.

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