690645-93-3 Usage
Uses
4-(((3-(Trifluoromethyl)phenyl)sulfonamido)methyl)benzoic Acid is a potent and selective inhibitor of the 11β-hydroxysteroid dehydrogenase type 1 with efficacy in diabetic ob/ob mice.
Check Digit Verification of cas no
The CAS Registry Mumber 690645-93-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,9,0,6,4 and 5 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 690645-93:
(8*6)+(7*9)+(6*0)+(5*6)+(4*4)+(3*5)+(2*9)+(1*3)=193
193 % 10 = 3
So 690645-93-3 is a valid CAS Registry Number.
690645-93-3Relevant articles and documents
4-(Phenylsulfonamidomethyl)benzamides as potent and selective inhibitors of the 11β-hydroxysteroid dehydrogenase type 1 with efficacy in diabetic ob/ob mice
Zhang, Xu,Zhou, Zhou,Yang, Huaiyu,Chen, Junhua,Feng, Ying,Du, Lili,Leng, Ying,Shen, Jianhua
supporting information; experimental part, p. 4455 - 4458 (2010/04/05)
Selective inhibitors of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) have considerable potential as treatments for type 2 diabetes. Presented herein are the syntheses, structure-activity relationships, and efficacy evaluation of 4-(phenylsulfonamido
