1-(([3-(TRIFLUOROMETHYL)PHENYL]SULFONYL)AMINO)CYCLOHEXANECARBOXYLIC ACID, also known as CFTR-inhibitor-II, is a chemical compound that has demonstrated potential therapeutic applications in the treatment of cystic fibrosis and related diseases. It functions as a potent inhibitor of the cystic fibrosis transmembrane conductance regulator (CFTR), which plays a crucial role in regulating ion transport across cell membranes. By modulating the activity of CFTR, 1-(([3-(TRIFLUOROMETHYL)PHENYL]SULFONYL)AMINO)CYCLOHEXANECARBOXYLIC ACID can potentially improve respiratory function in patients with cystic fibrosis.
690645-95-5
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Basic information
- Product Name: 1-(([3-(TRIFLUOROMETHYL)PHENYL]SULFONYL)AMINO)CYCLOHEXANECARBOXYLIC ACID
- Synonyms: 1-(([3-(TRIFLUOROMETHYL)PHENYL]SULFONYL)AMINO)CYCLOHEXANECARBOXYLIC ACID;CYCLOHEXANECARBOXYLIC ACID, 1-[[[3-(TRIFLUOROMETHYL)PHENYL]SULFONYL]AMINO]-;1-((3-(Trifluoromethyl)phenyl)sulfonamido)cyclohexane-1-carboxylic acid
- CAS NO:690645-95-5
- Molecular Formula: C14H16F3NO4S
- Molecular Weight: 351.34
- EINECS: N/A
- Product Categories: N/A
- Mol File: 690645-95-5.mol
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Chemical Properties
- Melting Point: 164-165℃
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: 1-(([3-(TRIFLUOROMETHYL)PHENYL]SULFONYL)AMINO)CYCLOHEXANECARBOXYLIC ACID(CAS DataBase Reference)
- NIST Chemistry Reference: 1-(([3-(TRIFLUOROMETHYL)PHENYL]SULFONYL)AMINO)CYCLOHEXANECARBOXYLIC ACID(690645-95-5)
- EPA Substance Registry System: 1-(([3-(TRIFLUOROMETHYL)PHENYL]SULFONYL)AMINO)CYCLOHEXANECARBOXYLIC ACID(690645-95-5)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 690645-95-5(Hazardous Substances Data)
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690645-95-5 Usage
Uses
Used in Pharmaceutical Industry:1-(([3-(TRIFLUOROMETHYL)PHENYL]SULFONYL)AMINO)CYCLOHEXANECARBOXYLIC ACID is used as a therapeutic agent for the treatment of cystic fibrosis. Its application is based on its ability to inhibit the CFTR protein, which is responsible for the regulation of ion transport across cell membranes. By targeting this protein, CFTR-inhibitor-II can potentially alleviate the symptoms associated with cystic fibrosis and improve the respiratory function of patients.
Additionally, due to its potential to regulate ion transport, 1-(([3-(TRIFLUOROMETHYL)PHENYL]SULFONYL)AMINO)CYCLOHEXANECARBOXYLIC ACID may also be used as a therapeutic agent for other disorders characterized by abnormal ion transport. However, further research is required to explore its potential applications in these areas.
Check Digit Verification of cas no
The CAS Registry Mumber 690645-95-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,9,0,6,4 and 5 respectively; the second part has 2 digits, 9 and 5 respectively.Calculate Digit Verification of CAS Registry Number 690645-95:
(8*6)+(7*9)+(6*0)+(5*6)+(4*4)+(3*5)+(2*9)+(1*5)=195
195 % 10 = 5
So 690645-95-5 is a valid CAS Registry Number.
690645-95-5 Well-known Company Product Price
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Alfa Aesar
(H34351) 1-[3-(Trifluoromethyl)phenylsulfonylamino]cyclohexanecarboxylic acid, 96%
690645-95-5
250mg
449.0CNY
- Detail
Alfa Aesar
(H34351) 1-[3-(Trifluoromethyl)phenylsulfonylamino]cyclohexanecarboxylic acid, 96%
690645-95-5
1g
1243.0CNY
- Detail
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690645-95-5Downstream Products
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1-(([3-(TRIFLUOROMETHYL)PHENYL]SULFONYL)AMINO)CYCLOHEXANECARBOXYLIC ACID
