690662-91-0

Usage

Uses

Used in Organic Synthesis:
3-(N-Benzylsulfamoyl)phenylboronic acid is used as a reagent for the formation of carbon-carbon and carbon-heteroatom bonds, playing a crucial role in various organic synthesis processes.
Used in Suzuki-Miyaura Cross-Coupling Reactions:
In the field of organic chemistry, 3-(N-Benzylsulfamoyl)phenylboronic acid is utilized as a boron source for the synthesis of arylboronic esters through Suzuki-Miyaura cross-coupling reactions, which are essential for creating new carbon-carbon bond formations.
Used in Pharmaceutical and Agrochemical Industries:
3-(N-Benzylsulfamoyl)phenylboronic acid is employed in the synthesis of a variety of pharmaceuticals and agrochemicals, leveraging its versatile reactivity and the ability to selectively functionalize aromatic compounds.
Used in Drug Development:
Due to its boronic acid functionality, 3-(N-Benzylsulfamoyl)phenylboronic acid has the potential for selective binding to biological targets, which makes it an interesting candidate in the development of new drugs and bioconjugates, contributing to the advancement of medicinal chemistry.

Upstream product

• 100-46-9 benzylamine 
• 374538-00-8 3-bromobenzeneboronic acid N-methyldiethanolamine cyclic ester 

Relevant academic research and scientific papers

Structure-activity relationship for aryl and heteroaryl boronic acid inhibitors of hormone-sensitive lipase

A range of aryl and heteroaryl boronic acids were tested for their in vitro hormone-sensitive lipase inhibitory properties. (2-Benzyloxy-5-fluorophenyl) boronic acid, (2-benzyloxy-5-chlorophenyl)boronic acid and 5-bromothiophene-2- boronic acid were found to be the most potent HSL inhibitors with IC 50 values of 140, 17 and 350 nM, respectively.

Halo sulfonyl aryl boronates

The present invention relates to halo sulfonyl aryl boronates of the general formula (I): wherein Arylene designates a carbocyclic or heterocyclic, aromatic ring system comprising 1-3 rings; R1, R2 and R3 are, independentl

HALO SULFONYL ARYL BORONATES

The present invention relates to halo sulfonyl aryl boronates of the general formula (I): wherein Arylene designates a carbocyclic or heterocyclic, aromatic ring system comprising 1-3 rings; R1, R2 and R3 are, independently, hydrogen, C1-6alkyl, C1-6alkoxy, halogen, nitro, cyano or phenyl;X is fluoro, chloro or bromo; and Y is a boroxine moiety attached via a bond from Arylene to one of the boron atoms of a boroxine ring which ring has a group of the formula -Arylene(R1)(R2)(R3)SO2X, wherein Arylene, R1, R2, R3 and X are as defined above, at each of the other two boron atoms of the boroxine ring, or Y is a boronic acid group or a boronic ester group.The invention also relates to the preparation of the compounds of formula (I) and to their use in organic synthesis.