690664-20-1

Usage

Uses

Used in Pharmaceutical Research:
2-Propenoic acid, 3-(2-amino-3-fluorophenyl)-, methyl ester, (2E)is used as an intermediate in the synthesis of pharmaceuticals for its potential to be developed into biologically active compounds.
Used in Organic Synthesis:
2-Propenoic acid, 3-(2-amino-3-fluorophenyl)-, methyl ester, (2E)is used as a building block in the creation of more complex organic molecules, contributing to the advancement of chemical research and development.
Used in Specialty Chemicals and Materials Production:
2-Propenoic acid, 3-(2-amino-3-fluorophenyl)-, methyl ester, (2E)may be utilized in the production of specialty chemicals and materials, where its unique properties can be leveraged for specific applications.

Upstream product

• 292638-85-8 acrylic acid methyl ester 
• 65896-11-9 2-bromo-6-fluoroaniline 
• 107-83-5 2-Methylpentane 

Downstream Products

• 690664-27-8 (2E)-3-{2-[(4-bromobenzoyl)amino]-3-fluorophenyl}-2-propenoic acid methyl ester 
• 791117-28-7 (2E)-3-{3-fluoro-2-[(triphenylphosphoranylidene)amino]phenyl}-propenoic acid methyl ester 
• 917389-34-5 (R)-methyl 2-(8-fluoro-3-(2-methoxy-5-(trifluoromethyl)phenyl)-2-(4-(3-methoxyphenyl)piperazin-1-yl)-3,4-dihydroquinazolin-4-yl)acetate 
• 917389-26-5 methyl-(E)-3-(3-fluoro-2-(3-(2-methoxy-5-(trifluoromethyl)phenyl)ureido)phenyl)acrylate 
• 917389-32-3 (S)-2-(8-fluoro-3-(2-methoxy-5-(trifluoromethyl)-phenyl)-2-(4-(3-methoxyphenyl)piperazin-1-yl)-3,4-dihydroquinazolin-4-yl)acetic acid 
• 852415-54-4 (2E)-3-fluoro-2-({[1-(4-fluoro-3-methyl)piperidine-4-yl]caxbonyl}amino)phenylacrylic acid methylester 

Relevant academic research and scientific papers

Asymmetric synthesis of letermovir using a novel phase-Transfer-catalyzed aza-michael reaction

The development of a concise asymmetric synthesis of the antiviral development candidate letermovir is reported, proceeding in 60% yield over a total of seven steps from commercially available materials. Key to the effectiveness of this process is a nove

Heterocyclyl-substituted dihydroquinazolines and their use as antiviral agents

The invention relates to heterocyclyl-substituted dihydroquinazolines of formula (I), to processes for their preparation, to medicaments containing them, and to methods for the treatment and/or prophylaxis of diseases, in particular, for use as anti-viral agents, in particular, against cytomegaloviruses.

Substituted Dihydroquinazolines II

The invention relates to substituted dihydroquinazolines and to a method for the production thereof, the use thereof for treating and/or preventing diseases and for producing drugs for treating and/or preventing diseases, in particular for the use of the inventive dihydroquinazolines in the form of antiviral agents, in particular against cytomegaloviruses.

SUBSTITUTED DIHYDROQUINAZOLINES II

The invention relates to substituted dihydroquinazolines and to a method for the production thereof, the use thereof for treating and/or preventing diseases and for producing drugs for treating and/or preventing diseases, in particular for the use of the inventive dihydroquinazolines in the form of antiviral agents, in particular against cytomegaloviruses.

SUBSTITUTED DIHYDROCHINAZOLINES HAVING ANTIVIRAL PROPERTIES

The invention relates to substituted dihydrochinazolines of formula (I), methods for the production thereof, and the use thereof for producing medicaments used for treating and/or preventing diseases, particularly as antiviral agents, especially against cytomegaloviruses.

SUBSTITUTED QUINAZOLINES AS ANTIVIRAL AGENTS, ESPECIALLY AGAINST CYTOMEGALOVIRUSES

The invention relates to substituted quinazolines and to methods for the production thereof, in addition to the use thereof in the production of medicaments for the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, especial

HETEROCYCLYL-SUBSTITUTED DIHYDROQUINAZOLINES AND USE THEREOF AS AN ANTIVIRAL AGENT

The invention relates to heterocyclyl-substituted dihydroquinazolines of formula (I), methods for the production and use thereof for the production of medicaments for the treatment and/or prophylaxis of diseases, in particular, for use as anti-viral agents, in particular, against cytomegaloviruses.