690686-34-1Relevant academic research and scientific papers
Synthesis and NMR studies of novel chromone-2-carboxamide derivatives
Gaspar, Alexandra,Cagide, Fernando,Quezada, Elias,Reis, Joana,Uriarte, Eugenio,Borges, Fernanda
, p. 251 - 254 (2013)
Chromones are heterocyclic compounds of natural or synthetic origin that possess relevant pharmacological activities. Versatile functionalization of the chromone nucleus allows attaining of a chemical diversity suitable to perform structure-activity relationships in drug discovery and development programs. Accordingly, the synthesis and identification of novel chromone carboxamide derivatives with electron-donating and electron-withdrawing substituents in different positions of the exocyclic ring are reported in this work. Their complete structural characterization was performed using one-dimensional and two-dimensional resonance techniques. The data acquired are useful for a prompt analysis of related compounds that encompass our integrated medicinal chemistry sketch. Copyright
