69076-99-9

Upstream product

• 71053-51-5 (4R)-2-[4-acetylthio-2-oxoazetidin-1-yl]-2-triphenylphosphoranylideneacetic acid p-nitrobenzyl ester 
• 86623-76-9 C₁₇H₂₁N₂O₉PS 
• 86623-75-8 (2-acetylsulfanyl-4-oxo-azetidin-1-yl)-oxo-acetic acid 4-nitro-benzyl ester 
• 81779-73-9 chloroxoacetic acid (4-nitrophenyl)methyl ester 
• 53390-60-6 4-Acetylthioazetidin-2-one 
• 72597-64-9 4'-nitrobenzyl-2-[4R-(2-benzthiazolyldithio)-2-oxo-1-azetidinyl]-3-methylsulphonyloxy crotonate 

Relevant academic research and scientific papers

NEW SYNTHESIS OF PENEMS VIA A REDUCTIVE CYCLIZATION REACTION OF OXALIMIDES WITH TRIALKYL PHOSPHITE

Treatment of the oxalimide 5 with triethyl phosphite formed the penem 3 and the triethoxyphosphonium ylide 7, presumably via the common carbene intermediate 10.Prolonged heating of 7 afforded 3 and its C-5 epimer.Similar reaction of the oxalimide 13 with

Synthesis of Penems by Ring Contraction of a 2-Thiacephem

2-Thiacephems prepared from penicillanic acid undergo ring contraction to penems with triphenylphosphine.

2-Methylpenem-3-carboxylic acid antibiotics

There is described the preparation of novel 2-penem-3-carboxylic acid compounds having the formula STR1 and easily cleavable esters and carboxylic acid salts thereof. The compounds of formula I, particularly the dextrorotatory isomers thereof, are potent