6908-01-6Relevant academic research and scientific papers
Functionalisation of Saturated Hydrocarbons. Part 13. Futher Studies on the Gif Oxidation of Cholestane Derivatives
Barton, Derek H. R.,Boivin, Jean,Lelandais, Patrick
, p. 463 - 468 (2007/10/02)
The oxidation of cholest-4-en-3-one by the GifIV system to give progesterone has been studied over the temperature range -40 to +80 deg C.The optimum temperature is ca. +20 deg C.Below 0 deg C the yield of progesterone diminishes and the formation of a new compound, 25-hydroxycholest-4-en-3-one, is observed.The latter has been synthesised from lithocholic acid.An unexpected major product of the oxidation was A-nor-5β-cholestan-3-one, identified by comparison with an authentic sample.
DESULFURATION OF STEROIDAL THIANS
Kasal, Alexander
, p. 3148 - 3159 (2007/10/02)
The reaction of 4-thia-5-cholesten-3-one (X) with Raney nickel in protic medium affords alcohol III, while A-nor-5β-cholestan-3-one (XXIII), A-bisnor-2,5-secocholestane (XXXI) and the esters of the type XVIII are formed as by-products.When aprotic medium
