691005-75-1Relevant academic research and scientific papers
Methanesulfonamide group at position-4 of the C-5-phenyl ring of 1,5-diarylpyrazole affords a potent class of cyclooxygenase-2 (COX-2) inhibitors
Singh, Sunil Kumar,Vobbalareddy, Saibaba,Shivaramakrishna, Samala,Krishnamraju,Rajjak, Shaikh Abdul,Casturi, Seshagiri Rao,Akhila, Vangoori,Rao, Yeleswarapu Koteswar
, p. 1683 - 1688 (2007/10/03)
The effect of methanesulfonamide (MeSO2NH) group on COX-2 inhibitory activity of 1,5-diarylpyrazole is described. While this group being at position-4 of the N1-phenyl ring was found to be ineffective, its installation at position-4
