69111-47-3Relevant academic research and scientific papers
Palladium-Catalyzed Synthesis of Indoles from 2-Nitrostyrenes
Izumi, Taeko,Soutome, Michihiko,Miura, Takashi
, p. 1625 - 1629 (2007/10/02)
In the presence of palladium salts, oxidation of 2-nitrostyrenes 1 with nitrous acid alkyl esters 2 resulted in the formation of 2-nitrophenylacetaldehyde dialkyl acetals 3.Reductive cyclization of the acetals 3 with iron powder in acetic acid afforded indoles 5 in good yield.
ALDEHYDE-ENAMINES FROM α-OXOCARBOXYLIC ACIDS. A FACILE AND GENERAL ROUTE TO ALDEHYDES VIA DECARBOXYLATION OF α-OXOCARBOXYLIC ACIDS CARRYING β-HYDROGENS
Stamos, Ioannis K.
, p. 459 - 462 (2007/10/02)
When α-oxocarboxylic acids carrying β-hydrogens are treated with a secondary amine in boiling benzene with azeotropic removal of water, they decarboxylate quantitatively to form aldehyde-enamines which subsequently are hydrolyzed to the corresponding aldehydes in high yields.
