Hydroxyproline, also known as 4-hydroxy-L-proline, is a non-proteinogenic amino acid that plays a crucial role in the structure and stability of proteins, particularly in collagen. It is an essential component of the human body, as it contributes to the formation of strong and flexible connective tissues, such as skin, tendons, and ligaments. Hydroxyproline is synthesized in the body from the amino acid L-proline through a process called hydroxylation, which involves the addition of a hydroxyl group. This modification enhances the stability of collagen fibers, making them more resistant to mechanical stress. In addition to its structural role, hydroxyproline has been studied for its potential therapeutic applications, such as in the treatment of certain connective tissue disorders and as a biomarker for collagen metabolism.
The CAS Registry Mumber 6912-67-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,9,1 and 2 respectively; the second part has 2 digits, 6 and 7 respectively. Calculate Digit Verification of CAS Registry Number 6912-67: (6*6)+(5*9)+(4*1)+(3*2)+(2*6)+(1*7)=110 110 % 10 = 0 So 6912-67-0 is a valid CAS Registry Number.
Bacterial collagen-like proteins differ from vertebrate collagens in that they do not contain hydroxyproline, which is seen as a characteristic of the vertebrate collagens, and which provides a significant contribution to the stability of the collagen triple-helix at body temperature. Despite th...detailed