69123-54-2Relevant academic research and scientific papers
Binding of Mono- and Dianions within Silver Thiazolylurea Tweezers and Capsules
Lee, Novia T. X.,Hicks, Jamie,Wallace, Karl J.,Turner, David R.
, p. 12535 - 12541 (2017)
A silver thiazolylurea complex, [Ag(TUTh)2]+, has been used as a host species for geometrically differently shaped mono- and dianions: trigonal planar (NO3-), tetrahedral (SO42-), and octah
Anticancer and antimicrobial activities of new thiazolyl-urea derivatives: gene expression, DNA damage, DNA fragmentation and SAR studies
Aboelenin, Mohamad M.,Mahrous, Karima F.,Othman, Abdelmageed M.,Sroor, Farid M.
, (2022/01/31)
The drug resistance became the major challenge in the antimicrobial and anticancer drugs therapy. Therefore, there is an urgent need to looking for new types of antimicrobial and anticancer agents. Herein we reported the synthesis and biological evaluatio
Selenium-catalyzed carbonylation of 2-aminothiazole with nitro aromatics to N-aryl-N′-2-thiazolylureas
Zhang, Xiaopeng,Tang, Zhaojing,Niu, Xueli,Li, Zhengwei,Fan, Xuesen,Zhang, Guisheng
supporting information, p. 5266 - 5270 (2016/11/11)
An efficient, economical, and phosgene-free procedure for the synthesis of N-aryl-N′-2-thiazolylureas is reported. With cheap and recyclable nonmetal selenium instead of noble metals as the catalyst, carbon monoxide instead of virulent phosgene as the carbonylation agent, the selenium-catalyzed carbonylation reaction of 2-aminothiazole can proceed smoothly in one-pot manner with a variety of nitro aromatics in the presence of triethylamine to afford the desired N-aryl-N′-2-thiazolylureas mostly in moderate to good yields. Selenium catalyst can be easily recovered due to its phase-transfer catalytic ability and reused without any significant degradation of its catalytic performance.
Structure-based design, synthesis and molecular modeling studies of thiazolyl urea derivatives as novel anti-parkinsonian agents
Azam, Faizul,Shrivastava, Anil Kumar,Mohan, Govind,Prasad, Medapati Vijaya Vara,Thangavel, Neelaveni
, p. 1057 - 1068,12 (2012/12/12)
Synthesis of 1-(substituted aryl)-3-(thiazol-2-yl)urea derivatives was undertaken as our efforts to discover novel antiparkinsonian agents with improved pharmacological profile in haloperidol-induced catalepsy and oxidative stress in mice. Furfuryl, 2- an
Structure-based design, synthesis and molecular modeling studies of thiazolyl urea derivatives as novel anti-parkinsonian agents
Azam, Faizul,Prasad, Medapati Vijaya Vara,Thangavel, Neelaveni,Shrivastava, Anil Kumar,Mohan, Govind
, p. 1057 - 1068 (2013/01/15)
Synthesis of 1-(substituted aryl)-3-(thiazol-2-yl)urea derivatives was undertaken as our efforts to discover novel antiparkinsonian agents with improved pharmacological profile in haloperidol-induced catalepsy and oxidative stress in mice. Furfuryl, 2- an
