691361-96-3Relevant academic research and scientific papers
Inhibitors of HCV NS5B polymerase: Synthesis and structure-activity relationships of N-alkyl-4-hydroxyquinolon-3-yl-benzothiadiazine sulfamides
Chris Krueger,Madigan, Darold L.,Jiang, Wen W.,Kati, Warren M.,Liu, Dachun,Liu, Yaya,Maring, Clarence J.,Masse, Sherie,McDaniel, Keith F.,Middleton, Tim,Mo, Hongmei,Molla, Akhteruzzaman,Montgomery, Debra,Pratt, John K.,Rockway, Todd W.,Zhang, Rong,Kempf, Dale J.
, p. 3367 - 3370 (2007/10/03)
Substituted N-alkyl-4-hydroxyquinolon-3-yl-benzothiadiazine sulfamides were investigated as inhibitors of genotype 1 HCV polymerase. Structure-activity relationship patterns for this class of compounds are discussed.
Anti-infective agents
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, (2008/06/13)
Compounds having the formula are hepatitis C(HCV) polymerase inhibitors. Also disclosed are a composition and method for inhibiting hepatitis C(HCV) polymerase, processes for making the compounds, and synthetic intermediates employed in the processes.
