69140-15-4Relevant academic research and scientific papers
Meiosis regulating compounds
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, (2008/06/13)
Sterol derivative compounds, structurally related to natural compounds which can be extracted from bull testes and from human follicular fluid, useful for regulating meiosis in oocytes and in male germ cells. Some of these compounds are useful in the trea
Meiosis regulating compounds
-
, (2008/06/13)
Sterol derivative compounds, structurally related to natural compounds which can be extracted from bull testes and from human follicular fluid, useful for regulating meiosis in oocytes and in male germ cells. Some of these compounds are useful in the trea
Synthesis of 3β-hydroxy-5α-cholest-8-en-7-one and 3β-hydroxy-5α-cholest-8-en-11-one: Evaluation as potential hypocholesterolemic agents
Parish,Nanduri,Seikel,Kohl,Nusbaum
, p. 407 - 418 (2007/10/02)
An efficient procedure for the chemical synthesis of 3β-hydroxy-5α-cholest-8-en-7-one and 3β-hydroxy-5α-cholest-8-en-11-one is described. These ketosterols have been shown to have possible significant hypocholesterolemic effects when fed to normal rats at
A New Route to Steroid Ring-c Aromatization from 7-Oxygenated Steroids
Anastasia, Mario,Ciuffreda, Pierangela,Puppo, Marina Del,Fiecchi, Alberto
, p. 587 - 590 (2007/10/02)
3β-Acetoxy-5α-cholesta-8,14-dien-7β-ol (3), 3β-acetoxy-8α,9α-epoxy-5α-cholestan-7β-ol (6a), and 3β-acetoxy-8α,14α-epoxy-5α-cholestan-7β-ol (8a) have been aromatized with hydrochloric acid in ethanol to afford a 9:1 mixture of 12-methyl-18-nor-5α,17β(H)-cholesta-8,11,13-trien-3β-ol (4) and 12-methyl-18-nor-5α-cholesta-8,11,13-trien-3β-ol (5).By the same acidic treatment 3β-acetoxy-8α,9α-epoxy-5α-cholestan-7α-ol (6c) generates 3β-hydroxy-5α-cholest-8-en-7-one (7a), and 3β-acetoxy-8α,14α-epoxy-5α-cholestan-7α-ol (8c) affords 3β-hydroxy-5α-cholest-8(14)-en-7-one (9a) accompanied by the previously unobserved 3β-hydroxy-5α-cholest-8(14)-en-15-one (10a).
