69155-80-2

Basic information

• Product Name: 7-Bromo-4-oxo-4H-chromene-3-carbaldehyde
• Synonyms: 7-bromo-4-oxo-4H-chromene-3-carbaldehyde;7-BroMochroMone-3-carboxaldehyde;3-Formyl-7-bromochromone;7-Bromo-4-oxo-4H-1-benzopyran-3-carboxaldehyde;7-Bromo-4-oxo-4H-chromene-3-carboxaldehyde
• CAS NO: 69155-80-2
• Molecular Formula: C₁₀H₅BrO₃
• Molecular Weight: 253.05
• Mol File: 69155-80-2.mol
• Article Data: 5

Chemical Properties

• Melting Point: 200-205°C
• Boiling Point: 365.7 °C at 760 mmHg
• Flash Point: 175 °C
• Appearance: /
• Density: 1.835
• CAS DataBase Reference: 7-Bromo-4-oxo-4H-chromene-3-carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 7-Bromo-4-oxo-4H-chromene-3-carbaldehyde(69155-80-2)
• EPA Substance Registry System: 7-Bromo-4-oxo-4H-chromene-3-carbaldehyde(69155-80-2)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• RIDADR: UN 2811 6.1 / PGIII
• WGK Germany: 3
• Hazardous Substances Data: 69155-80-2(Hazardous Substances Data)

Usage

General Description

7-Bromo-4-oxo-4H-chromene-3-carbaldehyde is a chemical compound with the molecular formula C10H5BrO3. It is a member of the chromene family, which are important structural motifs in medicinal chemistry and drug discovery. 7-Bromo-4-oxo-4H-chromene-3-carbaldehyde is a highly reactive aldehyde that contains a bromine atom and a carbonyl group attached to a chromene ring. It has been studied for its potential applications in organic synthesis and as a building block for the development of new pharmaceuticals. Its unique structure and reactivity make it a valuable tool for the creation of diverse chemical compounds with potential biological activity.

Upstream product

• 30186-18-6 4'-bromo-2'-hydroxyacetophenone 
• 68-12-2 N,N-dimethyl-formamide 

Relevant articles and documents

Identification of potent α-amylase inhibitors via dynamic combinatorial chemistry

In this study, we report for the first time the discovery of potent α-amylase inhibitors using principle of dynamic combinatorial chemistry. The best compound identified exhibited not only high inhibitory efficiency but also low cytotoxicity. The binding mode and possible mechanism are determined in the subsequent kinetic and molecular docking studies.

One pot and metal-free approach to 3-(2-Hydroxybenzoyl)-1-aza-anthraquinones

Herein, a direct strategy to synthesize 3-(2-hydroxybenzoyl)-1-aza-anthraquinones with excellent efficiency,mild conditions, and benign functional group compatibilitywas reported. Avariety of 3-formylchromone compounds were employed as compatible substrates and this protocol gave the 3-(2-hydroxybenzoyl)-1-aza-anthraquinone derivatives in good to excellent yields without inert gas and expensive transition metal catalysts. Some compounds displayed good anti-proliferative activities.

Direct construction of xanthene and benzophenone derivatives via Br?nsted acid controlled Diels-Alder reaction of 3-vinylchromones and arynes

A Br?nsted acid controlled Diels-Alder reaction of 3-vinylchromones with arynes has been developed. By employing different kinds and amounts of acid, 9-aryl-9H-xanthen-9-ols or ortho-hydroxybenzophenones could be controllably furnished in good yields in an atom- and step-economic manner.