69156-30-5

Upstream product

• 175277-99-3 2-chloro-4-fluorobenzenethiol 
• 2106-02-7 2-chloro-4-fluoroaniline 
• 85958-57-2 2-chloro-4-fluorobenzene-1-sulfonyl chloride 

Downstream Products

• 878799-13-4 2-chloro-N-[(2R)-3-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-2-hydroxypropyl]-4-fluorobenzenesulfonamide 
• 85958-14-1 4-Chloro-5-sulfamoyl-2-[(thiophen-2-ylmethyl)-amino]-benzenesulfonic acid; compound with C-thiophen-2-yl-methylamine 
• 85958-10-7 furfurylammonium 4-chloro-N-furfuryl-5-sulfamoylorthanilate 
• 85958-16-3 2-Benzylamino-4-chloro-5-sulfamoyl-benzenesulfonic acid; compound with benzylamine 
• 85958-58-3 phenyl 4-chloro-2-fluoro-5-sulfamoylbenzenesulfonale 
• 69156-32-7 C₉H₉ClFN₃O₄S 
• 69156-35-0 4-chloro-2-fluoro-5-sulfamoylbenzenesulfonic acid dihydrate 
• 69156-34-9 4-Chlor-2-fluor-5-sulfamoylbenzolsulfochlorid 
• 69202-53-5 C₉H₁₁ClFN₃O₂S 
• 69156-33-8 4-Chlor-2-fluor-5-sulfamoylanilin 
• 69156-31-6 C₉H₁₀ClFN₂O₂S 

Relevant academic research and scientific papers

A general iodine-mediated synthesis of primary sulfonamides from thiols and aqueous ammonia

A general and efficient methodology for preparing primary sulfonamides has been developed. In the presence of iodine as the catalyst and TBHP (70% in water) as the oxidant, a wide range of primary sulfonamides were prepared from the corresponding thiols and aqueous ammonia in moderate to good yields.

PYRAZINE DERIVATIVES AND USE AS PI3K INHIBITORS

The present invention is related to pyrazine derivatives of Formula (I) in particular for the treatment and/or prophylaxis of autoimmune disorders and/or inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, bacterial or viral infections, kidney diseases, platelet aggregation, cancer, transplantation, graft rejection or lung injuries.