69164-79-0 Usage
General Description
2-amino-4-[(2-chloroethyl)sulfamoyl]butanoic acid is a chemical compound with the molecular formula C6H12ClNO4S. It is a derivative of butanoic acid and contains an amino group, a chloroethyl group, and a sulfamoyl group. 2-amino-4-[(2-chloroethyl)sulfamoyl]butanoic acid is used as a pharmaceutical intermediate and is a potential anticancer agent due to its ability to inhibit the growth of tumor cells. It may also have potential applications in the treatment of other diseases such as cystic fibrosis and cardiovascular diseases. Additionally, research has indicated that this compound may have anti-inflammatory and analgesic properties, making it a potentially valuable tool for drug development.
Check Digit Verification of cas no
The CAS Registry Mumber 69164-79-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,9,1,6 and 4 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 69164-79:
(7*6)+(6*9)+(5*1)+(4*6)+(3*4)+(2*7)+(1*9)=160
160 % 10 = 0
So 69164-79-0 is a valid CAS Registry Number.
69164-79-0Relevant articles and documents
Potential antitumor agents via inhibitors of L-asparagine synthetase: substituted sulfonamides and sulfonyl hydrazides related to glutamine
Brynes,Fiorina,Cooney,Milman
, p. 1550 - 1553 (2007/10/13)
A series of 4-(substituted aminosulfonyl)- and 4-(substituted hydrazinosulfonyl)-2-aminobutanoic acids, compounds structurally related to glutamine, was synthesized as potential inhibitors of L-asparagine synthetase and subjected to screening as antitumor agents. Target amino acids were obtained by condensation of a blocked reactive sulfonyl chloride with the appropriate amine or hydrazide, followed by deblocking with hydrogen-palladium or liquid hydrogen fluoride-anisole. Neither the target compounds nor their protected precursors inhibited the enzyme from L5178Y/AR or prolonged the life of mice with P-388 lymphocytic leukemia. However, DL-4,4'-dithiobis[2-(benzyloxycarbonylamino)-butanoic acid], an intermediate in the synthesis of the target amino acids, exhibited 90% inhibition of L-asparagine synthetase at 10 mM.
