69169-33-1Relevant academic research and scientific papers
Catalytic hydroamination of unactivated olefins using a Co catalyst for complex molecule synthesis
Shigehisa, Hiroki,Koseki, Natsumi,Shimizu, Nao,Fujisawa, Mayu,Niitsu, Makoto,Hiroya, Kou
supporting information, p. 13534 - 13537 (2015/02/02)
Functional group tolerance is one of the important requirements for chemical reactions, especially for the synthesis of complex molecules. Herein, we report a mild, general, and functional group tolerant intramolecular hydroamination of unactivated olefins using a Co(salen) complex, an N-fluoropyridinium salt, and a disiloxane reagent. This method, which was carried out at room temperature (or 0 °C), afforded three-, five-, six-, and seven-membered ring nitrogen-containing heterocyclic compounds and was compatible with diverse functional groups.
Cu(I)-catalyzed intramolecular hydroamination of unactivated alkenes bearing a primary or secondary amino group in alcoholic solvents
Ohmiya, Hirohisa,Moriya, Toshimitsu,Sawamura, Masaya
supporting information; experimental part, p. 2145 - 2147 (2009/09/25)
The Cu-Xantphos system [Cu(O-t-Bu)-Xantphos, 10-15 mol%] catalyzes the intramolecular hydroamination of unactivated terminal alkenes bearing an unprotected aminoalkyl substituent in alcoholic solvents, giving pyrrolidine and piperidine derivatives in exce
